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    RNASEL ribonuclease L [ Gallus gallus (chicken) ]

    Gene ID: 424410, updated on 3-Dec-2024

    Summary

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    Symbol
    RNASELprovided by CGNC
    Full Name
    ribonuclease Lprovided by CGNC
    Primary source
    CGNC:2677
    See related
    Ensembl:ENSGALG00010009830
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See RNASEL in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (5610224..5615728)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (5622125..5627616)

    Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene regulator of G-protein signaling 8 Neighboring gene regulator of G-protein signaling 16 Neighboring gene regulator of G protein signaling like 1 Neighboring gene glutamate-ammonia ligase Neighboring gene zinc finger protein 648

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    2-5A-dependent ribonuclease
    Names
    ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
    NP_001026438.2
    XP_040560473.1
    XP_040560475.1
    XP_040560476.1
    XP_040560477.1
    XP_046778468.1
    XP_046778469.1
    XP_046778470.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031267.2 → NP_001026438.2  2-5A-dependent ribonuclease

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000237
      UniProtKB/TrEMBL
      A0A8V0XZ22, Q2PBC0
      Related
      ENSGALP00010013543.1, ENSGALT00010023471.1
      Conserved Domains (4) summary
      cd10423
      Location:576 → 687
      RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
      PHA03095
      Location:37 → 296
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:55 → 86
      ANK; ANK repeat [structural motif]
      cl21453
      Location:375 → 507
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5610224..5615728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040704539.2 → XP_040560473.1  2-5A-dependent ribonuclease isoform X1

      UniProtKB/TrEMBL
      A0A8V0XZ22, Q2PBC0
      Conserved Domains (4) summary
      cd10423
      Location:576 → 687
      RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
      PHA03095
      Location:37 → 296
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:55 → 86
      ANK; ANK repeat [structural motif]
      cl21453
      Location:375 → 507
      PKc_like; Protein Kinases, catalytic domain

    2. XM_040704543.2 → XP_040560477.1  2-5A-dependent ribonuclease isoform X1

      UniProtKB/TrEMBL
      A0A8V0XZ22, Q2PBC0
      Conserved Domains (4) summary
      cd10423
      Location:576 → 687
      RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
      PHA03095
      Location:37 → 296
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:55 → 86
      ANK; ANK repeat [structural motif]
      cl21453
      Location:375 → 507
      PKc_like; Protein Kinases, catalytic domain

    3. XM_040704541.2 → XP_040560475.1  2-5A-dependent ribonuclease isoform X1

      UniProtKB/TrEMBL
      A0A8V0XZ22, Q2PBC0
      Conserved Domains (4) summary
      cd10423
      Location:576 → 687
      RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
      PHA03095
      Location:37 → 296
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:55 → 86
      ANK; ANK repeat [structural motif]
      cl21453
      Location:375 → 507
      PKc_like; Protein Kinases, catalytic domain

    4. XM_040704542.2 → XP_040560476.1  2-5A-dependent ribonuclease isoform X1

      UniProtKB/TrEMBL
      A0A8V0XZ22, Q2PBC0
      Conserved Domains (4) summary
      cd10423
      Location:576 → 687
      RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
      PHA03095
      Location:37 → 296
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:55 → 86
      ANK; ANK repeat [structural motif]
      cl21453
      Location:375 → 507
      PKc_like; Protein Kinases, catalytic domain

    RNA

    1. XR_005861806.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5622125..5627616
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046922512.1 → XP_046778468.1  2-5A-dependent ribonuclease isoform X1

      UniProtKB/TrEMBL
      Q2PBC0

    2. XM_046922513.1 → XP_046778469.1  2-5A-dependent ribonuclease isoform X1

      UniProtKB/TrEMBL
      Q2PBC0

    3. XM_046922514.1 → XP_046778470.1  2-5A-dependent ribonuclease isoform X1

      UniProtKB/TrEMBL
      Q2PBC0

    RNA

    1. XR_006935391.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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