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    COMT catechol-O-methyltransferase [ Gallus gallus (chicken) ]

    Gene ID: 416783, updated on 3-Dec-2024

    Summary

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    Official Symbol
    COMTprovided by CGNC
    Official Full Name
    catechol-O-methyltransferaseprovided by CGNC
    Primary source
    CGNC:1439
    See related
    Ensembl:ENSGALG00010024592
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See COMT in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (1052138..1071868)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (1057694..1077390)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121106879 Neighboring gene T-box 1 Neighboring gene G protein subunit beta 1 like Neighboring gene thioredoxin reductase 2 Neighboring gene armadillo repeat gene deleted in velocardiofacial syndrome Neighboring gene transport and golgi organization 2 homolog Neighboring gene microRNA 1306 Neighboring gene DGCR8, microprocessor complex subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables catechol O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in catecholamine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in developmental process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in dopamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    catechol O-methyltransferase
    XP_001233014.1
    XP_004945544.1
    XP_004945545.1
    XP_004945546.1
    XP_015131166.1
    XP_040540207.1
    XP_040540208.1
    XP_040540210.1
    XP_040540211.1
    XP_040540212.1
    XP_040540213.1
    XP_046757162.1
    XP_046784269.1
    XP_415077.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1052138..1071868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_415077.8 → XP_415077.1  catechol O-methyltransferase

      See identical proteins and their annotated locations for XP_415077.1

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    2. XM_004945488.5 → XP_004945545.1  catechol O-methyltransferase

      See identical proteins and their annotated locations for XP_004945545.1

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    3. XM_004945489.5 → XP_004945546.1  catechol O-methyltransferase

      See identical proteins and their annotated locations for XP_004945546.1

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Related
      ENSGALP00010036757.1, ENSGALT00010059998.1
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    4. XM_004945487.5 → XP_004945544.1  catechol O-methyltransferase

      See identical proteins and their annotated locations for XP_004945544.1

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    5. XM_015275680.4 → XP_015131166.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    6. XM_046901206.1 → XP_046757162.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4

    7. XM_001233013.7 → XP_001233014.1  catechol O-methyltransferase

      See identical proteins and their annotated locations for XP_001233014.1

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1057694..1077390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040684274.2 → XP_040540208.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    2. XM_040684277.2 → XP_040540211.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    3. XM_040684279.2 → XP_040540213.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    4. XM_040684278.2 → XP_040540212.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    5. XM_040684276.2 → XP_040540210.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

    6. XM_046928313.1 → XP_046784269.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4

    7. XM_040684273.2 → XP_040540207.1  catechol O-methyltransferase

      UniProtKB/TrEMBL
      A0A8V0ZTB4
      Conserved Domains (1) summary
      COG4122
      Location:62 → 243
      YrrM; Predicted O-methyltransferase YrrM [General function prediction only]
    Nucleotide Protein Strain
    Heading Accession and Version

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