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    LOC109046196 dual specificity mitogen-activated protein kinase kinase 5-like [ Cyprinus carpio (common carp) ]

    Gene ID: 109046196, updated on 7-Dec-2023

    Summary

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    Gene symbol
    LOC109046196
    Gene description
    dual specificity mitogen-activated protein kinase kinase 5-like
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cyprinus carpio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Cyprininae; Cyprinus
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    Genomic context

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    See LOC109046196 in Genome Data Viewer
    Location:
    chromosome: A7
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    101 current ASM1834038v1 (GCF_018340385.1) A7 NC_056578.1 (19793487..19842264, complement)
    100 previous assembly common carp genome (GCF_000951615.1) 42 NC_031738.1 (3202838..3217737, complement)

    Chromosome A7 - NC_056578.1Genomic Context describing neighboring genes Neighboring gene E3 SUMO-protein ligase PIAS1-like Neighboring gene uncharacterized LOC109102387 Neighboring gene SKI family transcriptional corepressor 1 homolog-B-like Neighboring gene small nucleolar RNA SNORD19 Neighboring gene mothers against decapentaplegic homolog 3 Neighboring gene mothers against decapentaplegic homolog 6-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dual specificity mitogen-activated protein kinase kinase 5-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cyprinus carpio Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1834038v1 Primary Assembly

    Genomic

    1. NC_056578.1 Reference ASM1834038v1 Primary Assembly

      Range
      19793487..19842264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042760206.1 → XP_042616140.1  dual specificity mitogen-activated protein kinase kinase 5-like isoform X2

      UniProtKB/TrEMBL
      A0A8C2E750, A0A9Q9Y9J7
      Conserved Domains (2) summary
      cd06395
      Location:17 → 106
      PB1_Map2k5; PB1 domain is essential part of the mitogen-activated protein kinase kinase 5 (Map2k5, alias MEK5) one of the key member of the signaling kinases cascade which involved in angiogenesis and early cardiovascular development. The PB1 domain of Map2k5 ...
      cd06619
      Location:163 → 441
      PKc_MKK5; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 5

    2. XM_042760205.1 → XP_042616139.1  dual specificity mitogen-activated protein kinase kinase 5-like isoform X1

      UniProtKB/TrEMBL
      A0A8C2E750, A0A8C2GH19, A0A9J7ZT86
      Conserved Domains (2) summary
      cd06395
      Location:17 → 106
      PB1_Map2k5; PB1 domain is essential part of the mitogen-activated protein kinase kinase 5 (Map2k5, alias MEK5) one of the key member of the signaling kinases cascade which involved in angiogenesis and early cardiovascular development. The PB1 domain of Map2k5 ...
      cd06619
      Location:164 → 442
      PKc_MKK5; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 5

    3. XM_042760207.1 → XP_042616141.1  dual specificity mitogen-activated protein kinase kinase 5-like isoform X3

      UniProtKB/TrEMBL
      A0A8C0XUX6, A0A9Q9Y9M3
      Conserved Domains (2) summary
      cd06395
      Location:17 → 106
      PB1_Map2k5; PB1 domain is essential part of the mitogen-activated protein kinase kinase 5 (Map2k5, alias MEK5) one of the key member of the signaling kinases cascade which involved in angiogenesis and early cardiovascular development. The PB1 domain of Map2k5 ...
      cl21453
      Location:164 → 348
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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