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    OCRL OCRL inositol polyphosphate-5-phosphatase [ Chrysemys picta bellii (western painted turtle) ]

    Gene ID: 101937608, updated on 18-Nov-2024

    Summary

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    Gene symbol
    OCRL
    Gene description
    OCRL inositol polyphosphate-5-phosphatase
    See related
    Ensembl:ENSCPBG00000011986
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Chrysemys picta bellii (sub-species: bellii)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Chrysemys
    Orthologs
    human mouse all
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    Genomic context

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    See OCRL in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_05 current ASM1138683v2 (GCF_011386835.1) 9 NC_088799.1 (61294275..61327766)
    103 previous assembly Chrysemys_picta_BioNano-3.0.4 (GCF_000241765.4) 9 NC_056657.1 (41613687..41647546, complement)

    Chromosome 9 - NC_088799.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl cis/trans isomerase, NIMA-interacting 4 Neighboring gene ERCC excision repair 6 like, spindle assembly checkpoint helicase Neighboring gene uncharacterized LOC135973526 Neighboring gene uncharacterized LOC135973374 Neighboring gene uncharacterized LOC135973375

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol polyphosphate 5-phosphatase OCRL

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_011386835.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1138683v2

    Genomic

    1. NC_088799.1 Reference ASM1138683v2

      Range
      61294275..61327766
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_065557212.1 → XP_065413284.1  inositol polyphosphate 5-phosphatase OCRL isoform X1

      UniProtKB/TrEMBL
      A0AAJ7YKG1

    2. XM_065557213.1 → XP_065413285.1  inositol polyphosphate 5-phosphatase OCRL isoform X3

      UniProtKB/TrEMBL
      A0AAJ7YK37

    3. XM_065557214.1 → XP_065413286.1  inositol polyphosphate 5-phosphatase OCRL isoform X5

      UniProtKB/TrEMBL
      A0AAJ7YK53

    4. XM_008175168.4 → XP_008173390.2  inositol polyphosphate 5-phosphatase OCRL isoform X2

      UniProtKB/TrEMBL
      A0A8C3HD24, A0AAJ6WXB2
      Related
      ENSCPBP00000016252.1
      Conserved Domains (3) summary
      cd09093
      Location:238 → 531
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:666 → 895
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      pfam16726
      Location:14 → 112
      OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain

    5. XM_042853375.2 → XP_042709309.1  inositol polyphosphate 5-phosphatase OCRL isoform X4

      UniProtKB/TrEMBL
      A0A8C3HD24, A0AAJ7YK92
      Conserved Domains (3) summary
      cd09093
      Location:223 → 516
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:651 → 880
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      cl17171
      Location:6 → 94
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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