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    BMPR2 bone morphogenetic protein receptor type 2 [ Panthera leo (lion) ]

    Gene ID: 122226504, updated on 22-Mar-2024

    Summary

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    Gene symbol
    BMPR2
    Gene description
    bone morphogenetic protein receptor type 2
    See related
    EnsemblRapid:ENSPLXG00005028707
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Panthera leo
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
    Orthologs
    human mouse all
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    Genomic context

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    See BMPR2 in Genome Data Viewer
    Location:
    chromosome: C1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    100 current P.leo_Ple1_pat1.1 (GCF_018350215.1) C1 NC_056686.1 (187222007..187416947)

    Chromosome C1 - NC_056686.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L35a-like Neighboring gene 60S ribosomal protein L12-like Neighboring gene U6atac minor spliceosomal RNA Neighboring gene family with sequence similarity 117 member B Neighboring gene islet cell autoantigen 1 like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056686.1 Chromosome C1 Reference P.leo_Ple1_pat1.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transforming growth factor beta receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bone morphogenetic protein receptor type-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Panthera leo Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference P.leo_Ple1_pat1.1 Primary Assembly

    Genomic

    1. NC_056686.1 Reference P.leo_Ple1_pat1.1 Primary Assembly

      Range
      187222007..187416947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042949759.1 → XP_042805693.1  bone morphogenetic protein receptor type-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C8X9A2
      Related
      ENSPLXP00005038115.1, ENSPLXT00005059253.1
      Conserved Domains (2) summary
      cd14054
      Location:207 → 504
      STKc_BMPR2_AMHR2; Catalytic domain of the Serine/Threonine Kinases, Bone Morphogenetic Protein and Anti-Muellerian Hormone Type II Receptors
      pfam01064
      Location:48 → 127
      Activin_recp; Activin types I and II receptor domain

    2. XM_042949758.1 → XP_042805692.1  bone morphogenetic protein receptor type-2 isoform X1

      Conserved Domains (1) summary
      cd14054
      Location:274 → 571
      STKc_BMPR2_AMHR2; Catalytic domain of the Serine/Threonine Kinases, Bone Morphogenetic Protein and Anti-Muellerian Hormone Type II Receptors

    3. XM_042949760.1 → XP_042805694.1  bone morphogenetic protein receptor type-2 isoform X3

      Conserved Domains (1) summary
      cd14054
      Location:199 → 496
      STKc_BMPR2_AMHR2; Catalytic domain of the Serine/Threonine Kinases, Bone Morphogenetic Protein and Anti-Muellerian Hormone Type II Receptors

    4. XM_042949761.1 → XP_042805695.1  bone morphogenetic protein receptor type-2 isoform X4

      Conserved Domains (1) summary
      cd14054
      Location:186 → 483
      STKc_BMPR2_AMHR2; Catalytic domain of the Serine/Threonine Kinases, Bone Morphogenetic Protein and Anti-Muellerian Hormone Type II Receptors

    5. XM_042949762.1 → XP_042805696.1  bone morphogenetic protein receptor type-2 isoform X5

      Conserved Domains (1) summary
      cd14054
      Location:34 → 331
      STKc_BMPR2_AMHR2; Catalytic domain of the Serine/Threonine Kinases, Bone Morphogenetic Protein and Anti-Muellerian Hormone Type II Receptors
    Nucleotide Protein
    Heading Accession and Version

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