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    Cracdl capping protein inhibiting regulator of actin like [ Mus musculus (house mouse) ]

    Gene ID: 72097, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Cracdlprovided by MGI
    Official Full Name
    capping protein inhibiting regulator of actin likeprovided by MGI
    Primary source
    MGI:MGI:1919347
    See related
    Ensembl:ENSMUSG00000026090 AllianceGenome:MGI:1919347
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010300C02Rik
    Summary
    Is expressed in lung and testis. Orthologous to human CRACDL (CRACD like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 20.2), cortex adult (RPKM 19.8) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Cracdl in Genome Data Viewer
    Location:
    1 B; 1 15.57 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (37650758..37758905, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (37611676..37720089, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene mannoside acetylglucosaminyltransferase 4, isoenzyme A Neighboring gene G1 to S phase transition pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1541 Neighboring gene STARR-seq mESC enhancer starr_00677 Neighboring gene predicted gene, 39627 Neighboring gene STARR-positive B cell enhancer ABC_E5748 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:37642841-37643028 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:37643098-37643207 Neighboring gene RIKEN cDNA 4930556I23 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:37671888-37672102 Neighboring gene STARR-seq mESC enhancer starr_00679 Neighboring gene RIKEN cDNA 4930470B04 gene Neighboring gene STARR-seq mESC enhancer starr_00681 Neighboring gene STARR-seq mESC enhancer starr_00682 Neighboring gene predicted gene, 39628 Neighboring gene testis specific 10 Neighboring gene STARR-seq mESC enhancer starr_00684 Neighboring gene STARR-positive B cell enhancer mm9_chr1:37921599-37921900 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:37922129-37922238 Neighboring gene lipoyltransferase 1 Neighboring gene MIT, microtubule interacting and transport, domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis. Snider PL, et al. J Cardiovasc Dev Dis, 2019 Jun 22. PMID 31234534, Free PMC Article
    2. 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. Berggård T, et al. J Proteome Res, 2006 Mar. PMID 16512683
    3. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
    4. Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca(2+)/CaM) and CaM Kinase II (CaMKII) Binding Partner. Evans PR, et al. J Proteome Res, 2018 Apr 6. PMID 29518331, Free PMC Article
    5. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    CRACD-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001403619.1 → NP_001390548.1  CRACD-like protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC123068, AC140321

    2. NM_001403620.1 → NP_001390549.1  CRACD-like protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC123068, AC140321

    3. NM_001403621.1 → NP_001390550.1  CRACD-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC123068, AC140321
      UniProtKB/TrEMBL
      E9Q3M9

    4. NM_001403622.1 → NP_001390551.1  CRACD-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC123068, AC140321
      UniProtKB/TrEMBL
      E9Q3M9

    5. NM_028096.2 → NP_082372.1  CRACD-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC123068, AC140321
      Consensus CDS
      CCDS48242.1
      UniProtKB/TrEMBL
      E9Q3M9
      Related
      ENSMUSP00000123803.2, ENSMUST00000162875.8
      Conserved Domains (4) summary
      PTZ00436
      Location:500 → 628
      PTZ00436; 60S ribosomal protein L19-like protein; Provisional
      PHA03307
      Location:430 → 818
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07764
      Location:695 → 1039
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      pfam15262
      Location:145 → 243
      DUF4592; Domain of unknown function (DUF4592)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      37650758..37758905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496297.3 → XP_006496360.1  CRACD-like protein isoform X4

      See identical proteins and their annotated locations for XP_006496360.1

      Conserved Domains (4) summary
      PTZ00436
      Location:500 → 628
      PTZ00436; 60S ribosomal protein L19-like protein; Provisional
      PHA03307
      Location:430 → 818
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07764
      Location:695 → 1039
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      pfam15262
      Location:145 → 243
      DUF4592; Domain of unknown function (DUF4592)

    2. XM_006496292.5 → XP_006496355.2  CRACD-like protein isoform X2

      Conserved Domains (4) summary
      PTZ00436
      Location:528 → 656
      PTZ00436; 60S ribosomal protein L19-like protein; Provisional
      PHA03307
      Location:458 → 846
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07764
      Location:723 → 1067
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      pfam15262
      Location:173 → 271
      DUF4592; Domain of unknown function (DUF4592)

    3. XM_006496291.5 → XP_006496354.2  CRACD-like protein isoform X1

      Conserved Domains (4) summary
      PTZ00436
      Location:528 → 656
      PTZ00436; 60S ribosomal protein L19-like protein; Provisional
      PHA03307
      Location:458 → 846
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07764
      Location:723 → 1067
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      pfam15262
      Location:173 → 271
      DUF4592; Domain of unknown function (DUF4592)
    Nucleotide Protein Strain
    Heading Accession and Version

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