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    CRADD CASP2 and RIPK1 domain containing adaptor with death domain [ Gallus gallus (chicken) ]

    Gene ID: 417900, updated on 17-Aug-2024

    Summary

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    Symbol
    CRADDprovided by CGNC
    Full Name
    CASP2 and RIPK1 domain containing adaptor with death domainprovided by CGNC
    Primary source
    CGNC:8588
    See related
    Ensembl:ENSGALG00010010466
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CRADD in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (44954169..45032103)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (45305219..45383130)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107052984 Neighboring gene mitochondrial ribosomal protein L42 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC112533381 Neighboring gene suppressor of cytokine signaling 2 Neighboring gene myosin heavy chain IB-like Neighboring gene transfer RNA methionine (anticodon CAU) Neighboring gene plexin C1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables death domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protease binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    death domain-containing protein CRADD

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030748.2 → NP_001025919.1  death domain-containing protein CRADD isoform b

      See identical proteins and their annotated locations for NP_001025919.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      Q5F3I3
      Related
      ENSGALP00010014222.1, ENSGALT00010025019.1
      Conserved Domains (2) summary
      cd08319
      Location:114 → 196
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    2. NM_001397043.1 → NP_001383972.1  death domain-containing protein CRADD isoform a

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0Y761
      Related
      ENSGALP00010014220.1, ENSGALT00010025017.1
      Conserved Domains (2) summary
      cd08319
      Location:171 → 253
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    3. NM_001397044.1 → NP_001383973.1  death domain-containing protein CRADD isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      Q5F3I3
      Conserved Domains (2) summary
      cd08319
      Location:114 → 196
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    4. NM_001397045.1 → NP_001383974.1  death domain-containing protein CRADD isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      Q5F3I3
      Conserved Domains (2) summary
      cd08319
      Location:114 → 196
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      44954169..45032103
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040695938.2 → XP_040551872.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761
      Conserved Domains (2) summary
      cd08319
      Location:171 → 253
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    2. XM_040695932.2 → XP_040551866.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761
      Conserved Domains (2) summary
      cd08319
      Location:171 → 253
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    3. XM_040695934.2 → XP_040551868.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761
      Conserved Domains (2) summary
      cd08319
      Location:171 → 253
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    4. XM_040695936.2 → XP_040551870.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761
      Conserved Domains (2) summary
      cd08319
      Location:171 → 253
      Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
      cd08327
      Location:1 → 94
      CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      45305219..45383130
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046907337.1 → XP_046763293.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761

    2. XM_046907334.1 → XP_046763290.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761

    3. XM_046907335.1 → XP_046763291.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761

    4. XM_046907336.1 → XP_046763292.1  death domain-containing protein CRADD isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y761
    Nucleotide Protein Strain
    Heading Accession and Version

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