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    CG6321 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39233, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6321provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036117
    Locus tag
    Dmel_CG6321
    See related
    AllianceGenome:FB:FBgn0036117
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6321
    Summary
    Predicted to enable 2-aminoadipate transaminase activity. Predicted to be involved in biosynthetic process. Is expressed in several structures, including adult fat body; gland; and gut section. Orthologous to human AADAT (aminoadipate aminotransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6321 in Genome Data Viewer
    Location:
    68A3-68A3; 3-34 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11059437..11061224, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11052537..11054324, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44547 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45119 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Biogenesis of lysosome-related organelles complex 1, subunit 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila suppressor of underreplication protein binds to late-replicating regions of polytene chromosomes. Makunin IV, et al. Genetics, 2002 Mar. PMID 11901119, Free PMC Article
    2. The Recent De Novo Origin of Protein C-Termini. Andreatta ME, et al. Genome Biol Evol, 2015 May 21. PMID 26002864, Free PMC Article
    3. The circadian clock interacts with metabolic physiology to influence reproductive fitness. Xu K, et al. Cell Metab, 2011 Jun 8. PMID 21641546, Free PMC Article
    4. Analysis of Ras-induced overproliferation in Drosophila hemocytes. Asha H, et al. Genetics, 2003 Jan. PMID 12586708, Free PMC Article
    5. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 2-aminoadipate transaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 2-aminoadipate transaminase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables kynurenine-oxoglutarate transaminase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6321-PA
    NP_648426.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11059437..11061224 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140169.4 → NP_648426.1  uncharacterized protein Dmel_CG6321 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648426.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTD9
      Related
      FBpp0075971
      Conserved Domains (2) summary
      cd00609
      Location:27 → 407
      AAT_like; Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine ...
      COG0436
      Location:25 → 414
      AspB; Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTD9 Q9VTD9

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