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    CG9372 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40137, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9372provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036891
    Locus tag
    Dmel_CG9372
    See related
    AllianceGenome:FB:FBgn0036891
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    c-SP34; cSP34; Dmel\CG9372; SP34
    Summary
    Enables serine hydrolase activity. Involved in response to fungus. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic/larval posterior spiracle; posterior spiracle primordium; and sensory nervous system primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9372 in Genome Data Viewer
    Location:
    76B9-76B9; 3-45 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19606208..19608368)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19599308..19601468)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene lush Neighboring gene Lon protease Neighboring gene lethal (3) 76BDm Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class F Neighboring gene anti-silencing factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Drosophila Hemolymph, Serine Proteases Are the Major Gelatinases and Caseinases. Gatti JL, et al. Insects, 2024 Mar 28. PMID 38667364, Free PMC Article
    2. Peptidomic and proteomic analyses of the systemic immune response of Drosophila. Levy F, et al. Biochimie, 2004 Sep-Oct. PMID 15556270
    3. Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila. Nam HJ, et al. EMBO J, 2012 Mar 7. PMID 22227521, Free PMC Article
    4. Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation. Veillard F, et al. Biochimie, 2016 Mar. PMID 26453810
    5. High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy. Belozerov VE, et al. Mol Cell Biol, 2012 Sep. PMID 22801366, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in response to fungus HEP PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9372-PA
    NP_649132.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19606208..19608368
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140875.3 → NP_649132.1  uncharacterized protein Dmel_CG9372 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649132.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VW19
      Related
      FBpp0074713
      Conserved Domains (3) summary
      smart00680
      Location:87 → 132
      CLIP; Clip or disulphide knot domain
      smart00020
      Location:173 → 402
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:176 → 402
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VW19 Q9VW19

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