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    CG9922 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41708, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9922provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038196
    Locus tag
    Dmel_CG9922
    See related
    AllianceGenome:FB:FBgn0038196
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE55111; dHYPK; Dmel\CG9922; NEST:bs28g09
    Summary
    Predicted to be involved in negative regulation of apoptotic process and protein stabilization. Orthologous to human HYPK (huntingtin interacting protein K). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9922 in Genome Data Viewer
    Location:
    88A4-88A4; 3-54 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14035018..14036398, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9860740..9862120, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43460 Neighboring gene roadkill Neighboring gene transfer RNA:Serine-GCT 2-2 Neighboring gene Cytochrome P450 6d5 Neighboring gene uncharacterized protein Neighboring gene forkhead box, sub-group O

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The drosophila T-box transcription factor midline functions within Insulin/Akt and c-Jun-N terminal kinase stress-reactive signaling pathways to regulate interommatial bristle formation and cell survival. Chen QB, et al. Mech Dev, 2015 May. PMID 25748605, Free PMC Article
    2. Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms. Rathore OS, et al. Sci Rep, 2016 Feb 10. PMID 26861501, Free PMC Article
    3. A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. Saj A, et al. Dev Cell, 2010 May 18. PMID 20493818
    4. A Genome-Wide Screen for Dendritically Localized RNAs Identifies Genes Required for Dendrite Morphogenesis. Misra M, et al. G3 (Bethesda), 2016 Aug 9. PMID 27260999, Free PMC Article
    5. New components of Drosophila leg development identified through genome wide association studies. Grubbs N, et al. PLoS One, 2013. PMID 23560084, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9922-PA
    CG9922-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14035018..14036398 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275627.1 → NP_001262556.1  uncharacterized protein Dmel_CG9922, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262556.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFN9
      Conserved Domains (2) summary
      cd14361
      Location:82 → 122
      UBA_HYPK; UBA-like domain found in Huntingtin-interacting protein K (HYPK) and similar proteins
      cl00281
      Location:15 → 108
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...

    2. NM_142072.3 → NP_650329.1  uncharacterized protein Dmel_CG9922, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650329.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFN9
      Related
      FBpp0082333
      Conserved Domains (2) summary
      cd14361
      Location:82 → 122
      UBA_HYPK; UBA-like domain found in Huntingtin-interacting protein K (HYPK) and similar proteins
      cl00281
      Location:15 → 108
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFN9 Q9VFN9

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