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    TAF11L12 TATA-box binding protein associated factor 11 like 12 [ Homo sapiens (human) ]

    Gene ID: 112488739, updated on 4-Jan-2025

    Summary

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    Official Symbol
    TAF11L12provided by HGNC
    Official Full Name
    TATA-box binding protein associated factor 11 like 12provided by HGNC
    Primary source
    HGNC:HGNC:53855
    See related
    Ensembl:ENSG00000249156 AllianceGenome:HGNC:53855
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable protein heterodimerization activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See TAF11L12 in Genome Data Viewer
    Location:
    5p15.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (17610392..17612111)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (17610611..17612330)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (17610501..17612220)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:17597675-17598251 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:17598552-17599134 Neighboring gene TATA-box binding protein associated factor 11 like 10 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:17599135-17599717 Neighboring gene TATA-box binding protein associated factor 11 like 11 Neighboring gene H3 histone pseudogene 19 Neighboring gene H3 histone pseudogene 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development. Töhönen V, et al. Nat Commun, 2015 Sep 11. PMID 26360614, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See Variation Viewer (GRCh37.p13)

    General gene information

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    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    TATA-box-binding protein-associated factor 11-like protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401686.2 → NP_001388615.1  TATA-box-binding protein-associated factor 11-like protein 12

      Status: INFERRED

      Source sequence(s)
      AC233724
      Consensus CDS
      CCDS93698.1
      UniProtKB/Swiss-Prot
      A0A1W2PPW3
      UniProtKB/TrEMBL
      A0A1W2PRN6
      Related
      ENSP00000491758.1, ENST00000503184.2

    2. NM_001423536.1 → NP_001410465.1  TATA-box-binding protein-associated factor 11-like protein 12

      Status: INFERRED

      Source sequence(s)
      AC233724
      UniProtKB/Swiss-Prot
      A0A1W2PPW3
      UniProtKB/TrEMBL
      A0A1W2PRN6
      Related
      ENSP00000520475.1, ENST00000715555.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      17610392..17612111
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      17610611..17612330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A1W2PPW3.1 GenPept UniProtKB/Swiss-Prot:A0A1W2PPW3

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