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    NCOA2 nuclear receptor coactivator 2 [ Gallus gallus (chicken) ]

    Gene ID: 420176, updated on 3-Dec-2024

    Summary

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    Symbol
    NCOA2provided by CGNC
    Full Name
    nuclear receptor coactivator 2provided by CGNC
    Primary source
    CGNC:11634
    See related
    Ensembl:ENSGALG00010003775
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See NCOA2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (116214229..116406694, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (116217739..116410316, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109552 Neighboring gene PR/SET domain 14 Neighboring gene microRNA 1569-2 Neighboring gene uncharacterized LOC112531864 Neighboring gene translocation associated membrane protein 1-like 1 Neighboring gene lactamase beta 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to hormone stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear receptor coactivator 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      116214229..116406694 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025147995.3 → XP_025003763.2  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    2. XM_015282896.4 → XP_015138382.3  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Related
      ENSGALP00010005110.1, ENSGALT00010008730.1
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    3. XM_046928529.1 → XP_046784485.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    4. XM_015282898.4 → XP_015138384.3  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    5. XM_015282895.4 → XP_015138381.3  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    6. XM_025147992.3 → XP_025003760.2  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    7. XM_025147993.3 → XP_025003761.2  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    8. XM_046928512.1 → XP_046784468.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    9. XM_046928517.1 → XP_046784473.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    10. XM_046928537.1 → XP_046784493.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    11. XM_040691477.2 → XP_040547411.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    12. XM_046928545.1 → XP_046784501.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    13. XM_025147996.3 → XP_025003764.2  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    RNA

    1. XR_005856145.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      116217739..116410316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040662771.2 → XP_040518705.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    2. XM_040662764.2 → XP_040518698.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    3. XM_046912116.1 → XP_046768072.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    4. XM_040662769.2 → XP_040518703.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    5. XM_040662763.2 → XP_040518697.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    6. XM_040662767.2 → XP_040518701.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    7. XM_040662765.2 → XP_040518699.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    8. XM_046912114.1 → XP_046768070.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    9. XM_046912117.1 → XP_046768073.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    10. XM_040662772.2 → XP_040518706.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    11. XM_040662768.2 → XP_040518702.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    12. XM_046912118.1 → XP_046768074.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21

    13. XM_040662766.2 → XP_040518700.1  nuclear receptor coactivator 2

      UniProtKB/TrEMBL
      A0A8V0XHB4, A0A8V0XK21
      Conserved Domains (4) summary
      smart00091
      Location:117 → 174
      PAS; PAS domain
      pfam09606
      Location:964 → 1369
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam08430
      Location:1352 → 1451
      Forkhead_N; Forkhead N-terminal region
      cd18950
      Location:27 → 90
      bHLH-PAS_NCoA2_SRC2; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 2 (NCoA-2) and similar proteins

    RNA

    1. XR_005846079.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001012553.1: Suppressed sequence

      Description
      NM_001012553.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
    Nucleotide Protein Strain
    Heading Accession and Version

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