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    AK1 adenylate kinase 1 [ Gallus gallus (chicken) ]

    Gene ID: 396002, updated on 3-Dec-2024

    Summary

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    Symbol
    AK1provided by CGNC
    Full Name
    adenylate kinase 1provided by CGNC
    Primary source
    CGNC:49598
    See related
    Ensembl:ENSGALG00010028082
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See AK1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (5551849..5556720)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (4965537..4970410)

    Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Neighboring gene ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Neighboring gene endoglin Neighboring gene folylpolyglutamate synthase Neighboring gene cyclin dependent kinase 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Thiamin-triphosphate-synthesizing activity of mutant cytosolic adenylate kinases: significance of Arg-128 for substrate specificity. Shioda T, et al. Biochim Biophys Acta, 1993 Feb 13. PMID 8431472
    2. Structure and complete nucleotide sequence of the gene encoding chicken cytosolic adenylate kinase. Suminami Y, et al. J Biochem, 1988 Apr. PMID 2844738
    3. Isolation and characterization of cDNA for chicken muscle adenylate kinase. Kishi F, et al. J Biol Chem, 1986 Feb 25. PMID 2419325
    4. Evidence for in vivo synthesis of thiamin triphosphate by cytosolic adenylate kinase in chicken skeletal muscle. Miyoshi K, et al. J Biochem, 1990 Aug. PMID 2229026
    5. Mechanism of adenylate kinase. Are the essential lysines essential? Tian GC, et al. Biochemistry, 1990 May 8. PMID 2161682

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables adenylate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleoside diphosphate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ATP metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleoside triphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenylate kinase isoenzyme 1
    NP_990440.1
    XP_015134822.1
    XP_025011798.1
    XP_040504890.1
    XP_040504891.1
    XP_040504892.1
    XP_046757622.1
    XP_046784713.1
    XP_046784714.1
    XP_046784715.1
    XP_046784716.1
    XP_046784718.1
    XP_046784719.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205109.3 → NP_990440.1  adenylate kinase isoenzyme 1

      See identical proteins and their annotated locations for NP_990440.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000308
      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3
      Related
      ENSGALP00010041791.1, ENSGALT00010068048.1
      Conserved Domains (1) summary
      TIGR01360
      Location:7 → 194
      aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5551849..5556720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025156030.3 → XP_025011798.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3
      Conserved Domains (1) summary
      TIGR01360
      Location:7 → 194
      aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

    2. XM_040648956.2 → XP_040504890.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3
      Conserved Domains (1) summary
      TIGR01360
      Location:7 → 194
      aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

    3. XM_046901666.1 → XP_046757622.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3

    4. XM_040648958.2 → XP_040504892.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3
      Conserved Domains (1) summary
      TIGR01360
      Location:7 → 194
      aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

    5. XM_040648957.2 → XP_040504891.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3
      Related
      ENSGALP00010041789.1, ENSGALT00010068046.1
      Conserved Domains (1) summary
      TIGR01360
      Location:7 → 194
      aden_kin_iso1; adenylate kinase, isozyme 1 subfamily

    6. XM_015279336.3 → XP_015134822.1  adenylate kinase isoenzyme 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AJ72
      Related
      ENSGALP00010041788.1, ENSGALT00010068045.1
      Conserved Domains (2) summary
      TIGR01360
      Location:65 → 252
      aden_kin_iso1; adenylate kinase, isozyme 1 subfamily
      cd01428
      Location:69 → 241
      ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4965537..4970410
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046928758.1 → XP_046784714.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3

    2. XM_046928760.1 → XP_046784716.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3

    3. XM_046928759.1 → XP_046784715.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3

    4. XM_046928763.1 → XP_046784719.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3

    5. XM_046928762.1 → XP_046784718.1  adenylate kinase isoenzyme 1 isoform X2

      UniProtKB/Swiss-Prot
      P05081
      UniProtKB/TrEMBL
      A0A8V1AEY3

    6. XM_046928757.1 → XP_046784713.1  adenylate kinase isoenzyme 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AJ72
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P05081.1 GenPept UniProtKB/Swiss-Prot:P05081

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