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    shakB shaking B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33062, updated on 9-Dec-2024

    Summary

    Official Symbol
    shakBprovided by FlyBase
    Official Full Name
    shaking Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085387
    Locus tag
    Dmel_CG34358
    See related
    AllianceGenome:FB:FBgn0085387
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    2; 3; 6; CG12678; CG1321; CG15451; CG32508; CG34358; Dmel\CG34358; E81; FBpp0111481; inx8; Inx8; l(1)19Eb; l(1)LB21; l(1)R-10-14; l(1)R-10-3; l(1)R-10-7; l(1)R-9-29; l(1)TH73; l(1)W3; l(1)W3b; lincRNA.1031; nj-156; nj156; pas; Pas; pass; R-9-29; R9-29; Shak B; shak-B; Shak-B; SHAK-B; ShakB; shB; shkB; W3
    Old locus tag
    CG12678; CG32508; Dmel_CG12678; Dmel_CG32508
    Summary
    Enables gap junction channel activity and photoreceptor activity. Involved in several processes, including gap junction assembly; jump response; and phototransduction. Located in gap junction and plasma membrane. Is expressed in several structures, including ISN innervated muscle cell of A1-7; adult head; efferent neurons; ganglia; and midgut primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See shakB in Genome Data Viewer
    Location:
    19E2-19E5; 1-65 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20761071..20927050, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20632098..20798077, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44710 Neighboring gene long non-coding RNA:CR43838 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43193 Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Inhibitor-3 Neighboring gene uncharacterized protein Neighboring gene Niemann-Pick type C-1b

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    mobile_element

    • Loc: c20777807-20777766 mobile_element_type = transposon:INE-1{}5531
    • Loc: c20783281-20782766 mobile_element_type = transposon:INE-1{}5533
    • Loc: c20806472-20806130 mobile_element_type = transposon:INE-1{}5535
    • Loc: c20857088-20856882 mobile_element_type = transposon:INE-1{}5539
    • Loc: c20859803-20859728 mobile_element_type = transposon:gypsy12{}5557
    • Loc: c20880618-20880125 mobile_element_type = transposon:INE-1{}5541
    • Loc: c20895045-20894781 mobile_element_type = transposon:INE-1{}5545

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables gap junction channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables gap junction channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables photoreceptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell communication by electrical coupling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in gap junction assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intercellular transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in jump response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in phototransduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of membrane depolarization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to light stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in gap junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in gap junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in gap junction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    shaking B
    Names
    CG34358-PA
    CG34358-PC
    CG34358-PD
    CG34358-PE
    CG34358-PF
    CG34358-PG
    CG34358-PH
    CG34358-PI
    Shaking-B
    non-jumper-156
    passover
    passover-vital protein
    section 2
    section 3
    section 6
    shakB-PA
    shakB-PC
    shakB-PD
    shakB-PE
    shakB-PF
    shakB-PG
    shakB-PH
    shakB-PI
    shakingB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20761071..20927050 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258859.2NP_001245788.1  shaking B, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245788.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4LU30, M9NGR8
      Conserved Domains (1) summary
      pfam00876
      Location:24359
      Innexin; Innexin
    2. NM_001298574.1NP_001285503.1  shaking B, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285503.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4LU30, M9NGR8
      Conserved Domains (1) summary
      pfam00876
      Location:24359
      Innexin; Innexin
    3. NM_001258858.2NP_001245787.1  shaking B, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245787.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4LU30, M9NGR8
      Conserved Domains (1) summary
      pfam00876
      Location:24359
      Innexin; Innexin
    4. NM_078701.3NP_523425.2  shaking B, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523425.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4LU30
      Related
      FBpp0111482
      Conserved Domains (1) summary
      pfam00876
      Location:8343
      Innexin; Innexin
    5. NM_134566.3NP_608410.2  shaking B, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608410.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P33085
      Conserved Domains (1) summary
      pfam00876
      Location:179514
      Innexin; Innexin
    6. NM_001144750.2NP_001138222.1  shaking B, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138222.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P33085
      Conserved Domains (1) summary
      pfam00876
      Location:24274
      Innexin; Innexin
    7. NM_170660.2NP_728361.1  shaking B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728361.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8JUT3, B7Z104, P33085, Q1RKZ8, Q24011, Q24520, Q26432, Q9VRB9, Q9VRC0, Q9VRC2
      UniProtKB/TrEMBL
      G4LU30
      Related
      FBpp0111483
      Conserved Domains (1) summary
      pfam00876
      Location:20354
      Innexin; Innexin
    8. NM_001103568.3NP_001097038.2  shaking B, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097038.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P33085
      Conserved Domains (1) summary
      pfam00876
      Location:64298
      Innexin; Innexin