HCRT hypocretin neuropeptide precursor [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: HCRTprovided by VGNC
Official Full Name: hypocretin neuropeptide precursorprovided by VGNC
Primary source: VGNC:VGNC:29780
See related: BGD:BT11240; Ensembl:ENSBTAG00000000665
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 19

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	19	NC_037346.1 (42302320..42303565, complement)

Chromosome 19 - NC_037346.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The aim of the study was to determine by immunochemistry the expression of leptin, orexin A and orphanin FQ in the major salivary glands (parotid, submandibular and sublingual) of rat, sheep and cow.
Title: Immunohistochemical expression and distribution of orexin, orphanin and leptin in the major salivary glands of some mammals.
Orexin A was found in the beta cells of cattle, sheep, and swine where it may be implicated in the control of pancreatic activity.
Title: Immunohistochemical evidence of Orexin-A in the pancreatic beta cells of domestic animals.
first evidence for the expression of oxA and ox1R in the vestibular glands of mammalian genital tract
Title: Expression of orexin A and its receptor 1 in the vestibular glands of the cattle genital tract.
locally synthesized in the urethroprostatic complex
Title: Expression of orexin A and its receptor 1 in the bovine urethroprostatic complex.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables neuropeptide hormone activity	IEA Inferred from Electronic Annotation more info	PubMed
enables type 1 orexin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables type 2 orexin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in eating behavior	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neuropeptide signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transmission of nerve impulse	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of neurotransmitter secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to starvation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sleep	IEA Inferred from Electronic Annotation more info	PubMed
involved_in temperature homeostasis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: hypocretin neuropeptide precursor

Names: hcrt1; hypocretin (orexin) neuropeptide; hypocretin-1; orexin; orexin-A; prepro-orexin; preprohypocretin

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.