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    parC subunit A of DNA topoisomerase IV (ATP-dependent) [ Bacillus subtilis subsp. subtilis str. 168 ]

    Gene ID: 937107, updated on 6-Oct-2023

    Summary

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    Gene symbol
    parC
    Gene description
    subunit A of DNA topoisomerase IV (ATP-dependent)
    Locus tag
    BSU_18100
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
    Lineage
    Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
    Old locus tag
    BSU18100
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    Genomic context

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    Sequence:
    NC_000964.3 (1935448..1937868)

    NC_000964.3Genomic Context describing neighboring genes Neighboring gene putative acyl-CoA-binding protein Neighboring gene subunit B of DNA topoisomerase IV (ATP-dependent) Neighboring gene pseudo Neighboring gene pseudo Neighboring gene H+/Na+:nitrogen-donor aminoacid symporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000964.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis. Reuß DR, et al. Nucleic Acids Res, 2019 Jun 4. PMID 30957856, Free PMC Article
    2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
    3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
    4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
    5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. topoisomerase IV at increased expression is necessary and sufficient to take over the function of type 1A topoisomerases
      Title: Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    subunit A of DNA topoisomerase IV (ATP-dependent)
    NP_389692.2
    • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9539793, 12682299, 16267290, 16272394, 24440393; Product type e: enzyme

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000964.3 Reference assembly

      Range
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_389692.2 subunit A of DNA topoisomerase IV (ATP-dependent) [Bacillus subtilis subsp. subtilis str. 168]

      See identical proteins and their annotated locations for NP_389692.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0D1L394
      Conserved Domains (2) summary
      TIGR01061
      Location:7 → 744
      parC_Gpos; DNA topoisomerase IV, A subunit, Gram-positive
      sd00041
      Location:504 → 546
      GyrA-ParC_C; GyrA_CTD repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q45066.2

    Gene LinkOut

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    Other Literature Sources
    Molecular Biology Databases