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    Taf12L TBP-associated factor 30kD subunit alpha-2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33672, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Taf12Lprovided by FlyBase
    Official Full Name
    TBP-associated factor 30kD subunit alpha-2provided by FlyBase
    Primary source
    FLYBASE:FBgn0031623
    Locus tag
    Dmel_CG15632
    See related
    AllianceGenome:FB:FBgn0031623
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15632; Dmel\CG15632; dmTAF12b; dmTAF12L; dTAF12; dTAF12L; dTAF[[II]]30a; dTAF[[II]]30alpha-2; rye; Rye; TAF; TAF12L; Taf30alpha-2; TAF30alpha-2; TAF[[II]]; TFIID
    Summary
    Enables protein heterodimerization activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Located in male germ cell nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Taf12L in Genome Data Viewer
    Location:
    25A3-25A3; 2-13 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4700835..4701485, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4700835..4701485, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Early boundary activity 3 Neighboring gene uncharacterized protein Neighboring gene decima Neighboring gene uncharacterized protein Neighboring gene factor of interpulse interval Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of the testis TAFs of Drosophila. Li VC, et al. Mol Biol Evol, 2009 May. PMID 19244474, Free PMC Article
    2. Approaches to defining the ancestral eukaryotic protein complexome. Ceulemans H, et al. Bioessays, 2006 Mar. PMID 16479579
    3. An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline. Smolko AE, et al. Development, 2020 Sep 11. PMID 32816970, Free PMC Article
    4. Relocation facilitates the acquisition of short cis-regulatory regions that drive the expression of retrogenes during spermatogenesis in Drosophila. Sorourian M, et al. Mol Biol Evol, 2014 Aug. PMID 24855141, Free PMC Article
    5. Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation. Goodrich JA, et al. Nat Rev Genet, 2010 Aug. PMID 20628347, Free PMC Article

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein heterodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in male germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TBP-associated factor 30kD subunit alpha-2
    Names
    CG15632-PA
    TBP-associated factor
    TBP-associated factor subunit alpha-2
    Taf12L-PA
    ryan express

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4700835..4701485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135008.4 → NP_608852.1  TBP-associated factor 30kD subunit alpha-2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608852.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5UEC2, Q9VR21
      Related
      FBpp0077111
      Conserved Domains (1) summary
      pfam03847
      Location:67 → 133
      TFIID_20kDa; Transcription initiation factor TFIID subunit A
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5UEC2 Q5UEC2
    Q6AWQ5 Q6AWQ5
    Q9VR21 Q9VR21

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