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    Smyd3 SET and MYND domain containing, class 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44554, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Smyd3provided by FlyBase
    Official Full Name
    SET and MYND domain containing, class 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0011566
    Locus tag
    Dmel_CG13761
    See related
    AllianceGenome:FB:FBgn0011566
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Bzd; CG13761; Dmel\CG13761; EG:BACR7C10.4
    Summary
    Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be active in nucleus. Orthologous to several human genes including SMYD3 (SET and MYND domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Smyd3 in Genome Data Viewer
    Location:
    3A7-3A7; 1-1 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2606680..2608876, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2500713..2502909, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene egghead Neighboring gene Kinesin-like protein at 3A Neighboring gene Zeste-white 10 Neighboring gene eukaryotic translation initiation factor 3 subunit g1 Neighboring gene Tetraspanin 3A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species. Calpena E, et al. PLoS One, 2015. PMID 26230726, Free PMC Article
    2. DEAF-1 function is essential for the early embryonic development of Drosophila. Veraksa A, et al. Genesis, 2002 Jun. PMID 12112874
    3. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2015 Jul 21. PMID 26199285, Free PMC Article
    4. TRF4, the novel TBP-related protein of Drosophila melanogaster, is concentrated at the endoplasmic reticulum and copurifies with proteins participating in the processes associated with endoplasmic reticulum. Kurshakova MM, et al. J Cell Biochem, 2019 May. PMID 30426565
    5. Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC). Borrás T, et al. Genetics, 2003 Feb. PMID 12618402, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-lysine N-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SET and MYND domain containing, class 3
    Names
    CG13761-PB
    Smyd3-PB
    buzidau

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2606680..2608876 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080029.4 → NP_524768.2  SET and MYND domain containing, class 3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524768.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRV6, Q9NF43, Q9W4X8
      Related
      FBpp0070431
      Conserved Domains (2) summary
      pfam01753
      Location:60 → 97
      zf-MYND; MYND finger
      pfam13424
      Location:377 → 440
      TPR_12; Tetratricopeptide repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MRV6 Q8MRV6
    Q9W4X8 Q9W4X8

    Gene LinkOut

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