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    Tsp47F Tetraspanin 47F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36230, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tsp47Fprovided by FlyBase
    Official Full Name
    Tetraspanin 47Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033629
    Locus tag
    Dmel_CG9033
    See related
    AllianceGenome:FB:FBgn0033629
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9033; Dm.Tsp47F; Dmel\CG9033; tsp47F
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human CD63 (CD63 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tsp47F in Genome Data Viewer
    Location:
    47F7-47F7; 2-64 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11377193..11379177, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7264698..7266682, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Translocon-associated protein delta Neighboring gene uncharacterized protein Neighboring gene Superoxide dismutase 3 Neighboring gene sprite Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular Basis for Cephalic Mechanosensitivity of Drosophila Larvae. Zhang Z, et al. Neurosci Bull, 2020 Sep. PMID 32761438, Free PMC Article
    2. Genetic identification of intracellular trafficking regulators involved in Notch-dependent binary cell fate acquisition following asymmetric cell division. Le Bras S, et al. J Cell Sci, 2012 Oct 15. PMID 22825875
    3. Polarized sorting of Patched enables cytoneme-mediated Hedgehog reception in the Drosophila wing disc. González-Méndez L, et al. EMBO J, 2020 Jun 2. PMID 32311148, Free PMC Article
    4. Involvement of CD9 and PDGFR in migration is evolutionarily conserved from Drosophila glia to human glioma. Jeibmann A, et al. J Neurooncol, 2015 Sep. PMID 26224160
    5. Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Fradkin LG, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370414, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tetraspanin 47F
    Names
    CG9033-PB
    Tsp47F-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11377193..11379177 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165828.3 → NP_725044.1  tetraspanin 47F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725044.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8K7
      Related
      FBpp0087248
      Conserved Domains (2) summary
      cd03156
      Location:102 → 205
      uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:9 → 233
      Tetraspannin; Tetraspanin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z8K7 A1Z8K7

    Gene LinkOut

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