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    CG8841 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36336, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8841provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033713
    Locus tag
    Dmel_CG8841
    See related
    AllianceGenome:FB:FBgn0033713
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmc1; Dmel\CG8841
    Summary
    Predicted to be involved in intracellular protein transport. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi medial cisterna; Golgi trans cisterna; and membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 105. Orthologous to human HID1 (HID1 domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8841 in Genome Data Viewer
    Location:
    48F8-48F8; 2-66 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12322507..12326258, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8210012..8213763, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44316 Neighboring gene mitochondrial translation initiation factor 3 Neighboring gene gartenzwerg Neighboring gene transfer RNA:Histidine-GTG 1-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1. Barclay SS, et al. Hum Mol Genet, 2014 Mar 1. PMID 24179173
    2. The mRNA transportome of the BicD/Egl transport machinery. Vazquez-Pianzola P, et al. RNA Biol, 2017 Jan 2. PMID 27801632, Free PMC Article
    3. Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene. Kumar S, et al. Sci Rep, 2016 Nov 7. PMID 27819340, Free PMC Article
    4. Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates. Olson JM, et al. G3 (Bethesda), 2019 Nov 5. PMID 31690598, Free PMC Article
    5. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in Golgi medial cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi trans cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8841-PA
    CG8841-PB
    CG8841-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12322507..12326258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165880.1 → NP_725132.1  uncharacterized protein Dmel_CG8841, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725132.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E9B5, Q52KA6
      Related
      FBpp0087072, FBtr0087964
      Conserved Domains (1) summary
      pfam12722
      Location:1 → 834
      Hid1; High-temperature-induced dauer-formation protein

    2. NM_136916.2 → NP_610760.1  uncharacterized protein Dmel_CG8841, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610760.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E9B5, Q52KA6
      Related
      FBpp0087073, FBtr0087965
      Conserved Domains (1) summary
      pfam12722
      Location:1 → 834
      Hid1; High-temperature-induced dauer-formation protein

    3. NM_165879.2 → NP_725131.1  uncharacterized protein Dmel_CG8841, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725131.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E9B5, Q52KA6
      Related
      FBpp0087074
      Conserved Domains (1) summary
      pfam12722
      Location:1 → 834
      Hid1; High-temperature-induced dauer-formation protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E9B5 Q0E9B5

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