U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    osta-2 Organic solute transporter alpha-like protein 2 [ Caenorhabditis elegans ]

    Gene ID: 173966, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    osta-2
    Official Full Name
    Organic solute transporter alpha-like protein 2
    Primary source
    WormBase:WBGene00015942
    Locus tag
    CELE_C18A3.4
    See related
    AllianceGenome:WB:WBGene00015942
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in neurons. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Orthologous to human SLC51A (solute carrier family 51 member A). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See osta-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (5707691..5712351)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cytotoxic granule-associated RNA binding protein tiar-1;RRM domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Late ELOngation arrest Neighboring gene putative rRNA-processing protein EBP2 homolog

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Organic solute transporter alpha-like protein 2
    NP_741003.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5707691..5712351
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171004.7 → NP_741003.1  Organic solute transporter alpha-like protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741003.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18071, Q8IG51, Q95QV9
      Conserved Domains (1) summary
      pfam03619
      Location:46 → 303
      Solute_trans_a; Organic solute transporter Ostalpha

    RNA

    1. NR_136363.1 RNA Sequence

      Status: REVIEWED

    2. NR_136362.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q18071.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools