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    grx3 CIA machinery monothiol glutaredoxin Grx3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539000, updated on 18-Sep-2024

    Summary

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    Official Symbol
    grx3
    Official Full Name
    CIA machinery monothiol glutaredoxin Grx3
    Primary source
    PomBase:SPCC1450.06c
    Locus tag
    SPOM_SPCC1450.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See grx3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1735279..1736106, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribonucleoprotein complex protein Utp502 Neighboring gene ncRNA Neighboring gene translation elongation factor EF-1 beta subunit, guanyl-nucleotide exchange factor (eEF1B) Neighboring gene ncRNA Neighboring gene mediator complex subunit Med19 Neighboring gene ncRNA Neighboring gene D-amino acid oxidase Neighboring gene ncRNA Neighboring gene wtf antidote-like meiotic drive suppressor Wtf16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization and regulation of the gene encoding monothiol glutaredoxin 3 in the fission yeast Schizosaccharomyces pombe. Moon JS, et al. Mol Cells, 2005 Aug 31. PMID 16258244
    2. Localization and function of three monothiol glutaredoxins in Schizosaccharomyces pombe. Chung WH, et al. Biochem Biophys Res Commun, 2005 May 6. PMID 15796926
    3. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
    4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutathione disulfide oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione disulfide oxidoreductase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus HDA PubMed 
    is_active_in Golgi lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cis-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in fungal-type vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nuclear outer membrane-endoplasmic reticulum membrane network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CIA machinery monothiol glutaredoxin Grx3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1735279..1736106 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023295.3 → NP_588305.1  CIA machinery monothiol glutaredoxin Grx3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588305.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q76PC6, Q9UU55, Q9Y7N3
      Conserved Domains (1) summary
      TIGR02180
      Location:68 → 152
      GRX_euk; Glutaredoxin
    Nucleotide Protein
    Heading Accession and Version

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