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    Spink8 serine peptidase inhibitor, Kazal type 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301016, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Spink8provided by RGD
    Official Full Name
    serine peptidase inhibitor, Kazal type 8provided by RGD
    Primary source
    RGD:1307150
    See related
    EnsemblRapid:ENSRNOG00000037199 AllianceGenome:RGD:1307150
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307150
    Summary
    Orthologous to human SPINK8 (serine peptidase inhibitor Kazal type 8 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 1048.7) and Testes (RPKM 147.3) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Spink8 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (118686362..118707449)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (109814062..109828994)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (117903088..117917821)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene plexin B1 Neighboring gene cytochrome c oxidase subunit 6C, pseudogene 2 Neighboring gene F-box and WD repeat domain containing 12 Neighboring gene NME/NM23 nucleoside diphosphate kinase 6 Neighboring gene cathelicidin antimicrobial peptide

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    serine protease inhibitor Kazal-type 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106860.1 → NP_001100330.1  serine protease inhibitor Kazal-type 8

      See identical proteins and their annotated locations for NP_001100330.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473954
      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6
      Conserved Domains (1) summary
      cd01327
      Location:47 → 96
      KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      118686362..118707449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265265.1 → XP_063121335.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6

    2. XM_063265266.1 → XP_063121336.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6

    3. XM_063265268.1 → XP_063121338.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6
      Related
      ENSRNOP00000053026.2, ENSRNOT00000056180.5

    4. XM_063265267.1 → XP_063121337.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6

    5. XM_063265269.1 → XP_063121339.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6

    6. XM_008766512.4 → XP_008764734.1  serine protease inhibitor Kazal-type 8 isoform X1

      See identical proteins and their annotated locations for XP_008764734.1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6
      Conserved Domains (1) summary
      cd01327
      Location:47 → 96
      KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...

    7. XM_017595595.3 → XP_017451084.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6
      Conserved Domains (1) summary
      cd01327
      Location:47 → 96
      KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...

    8. XM_063265264.1 → XP_063121334.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6

    9. XM_039081246.2 → XP_038937174.1  serine protease inhibitor Kazal-type 8 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A5J3, A6I3B8, A6I3B9, D3ZHW6
      Conserved Domains (1) summary
      cd01327
      Location:47 → 96
      KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...
    Nucleotide Protein Strain
    Heading Accession and Version

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