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    Cstpp1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295930, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cstpp1provided by RGD
    Official Full Name
    centriolar satellite-associated tubulin polyglutamylase complex regulator 1provided by RGD
    Primary source
    RGD:1309540
    See related
    EnsemblRapid:ENSRNOG00000014798 AllianceGenome:RGD:1309540
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309540
    Summary
    Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in regulation of protein complex stability. Predicted to be located in cytoplasm and microtubule. Predicted to be active in centriolar satellite. Orthologous to human CSTPP1 (centriolar satellite-associated tubulin polyglutamylase complex regulator 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 207.8), Testes (RPKM 106.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cstpp1 in Genome Data Viewer
    Location:
    3q24
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (97704176..97872084, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (77247393..77416307, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (80092589..80349249, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene acid phosphatase 2, lysosomal Neighboring gene damage specific DNA binding protein 2 Neighboring gene protein kinase C and casein kinase substrate in neurons 3 Neighboring gene ARF GTPase activating protein 2 Neighboring gene uncharacterized LOC120101910 Neighboring gene U2 spliceosomal RNA Neighboring gene LDL receptor related protein 4 Neighboring gene uncharacterized LOC120101912 Neighboring gene uncharacterized LOC134486122

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of protein complex stability ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in centriolar satellite IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    centriolar satellite-associated tubulin polyglutamylase complex regulator 1
    Names
    UPF0705 protein C11orf49 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013918.2 → NP_001013940.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform 1

      See identical proteins and their annotated locations for NP_001013940.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      Q5M9F0
      UniProtKB/TrEMBL
      A0A8L2QM69
      Related
      ENSRNOP00000083495.2, ENSRNOT00000115913.2

    2. NM_001429938.1 → NP_001416867.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    3. NM_001429939.1 → NP_001416868.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I5ZL69, A0A8L2QM69

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      97704176..97872084 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017591556.3 → XP_017447045.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X1

      Related
      ENSRNOP00000078631.2, ENSRNOT00000108550.2

    2. XM_039104523.2 → XP_038960451.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X5

    3. XM_063283294.1 → XP_063139364.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X6

    4. XM_039104520.2 → XP_038960448.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AK47

    5. XM_039104525.2 → XP_038960453.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X7

    6. XM_039104521.2 → XP_038960449.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AK47

    7. XM_063283295.1 → XP_063139365.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X7

    8. XM_063283296.1 → XP_063139366.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X8

    9. XM_039104522.2 → XP_038960450.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5M9F0.1 GenPept UniProtKB/Swiss-Prot:Q5M9F0

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