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    PIM1 Pim-1 proto-oncogene, serine/threonine kinase [ Bos taurus (domestic cattle) ]

    Gene ID: 281402, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PIM1provided by VGNC
    Official Full Name
    Pim-1 proto-oncogene, serine/threonine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:32899
    See related
    BGD:BT10565; Ensembl:ENSBTAG00000000396
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PIM1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (11066555..11071948)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132343602 Neighboring gene uncharacterized LOC101907794 Neighboring gene transmembrane protein 217B Neighboring gene transmembrane protein 217

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. cDNA cloning, sequencing and characterization of bovine pim-1. Wang Z, et al. Vet Immunol Immunopathol, 2001 Jan 26. PMID 11182156
    2. A radiation hybrid map of BTA23: identification of a chromosomal rearrangement leading to separation of the cattle MHC class II subregions. Band M, et al. Genomics, 1998 Nov 1. PMID 9799592
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein autophosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase pim-1
    Names
    non-specific serine/threonine protein kinase
    pim-1 oncogene
    proto-oncogene serine/threonine-protein kinase pim-1
    NP_776569.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174144.2 → NP_776569.1  serine/threonine-protein kinase pim-1

      See identical proteins and their annotated locations for NP_776569.1

      Status: PROVISIONAL

      Source sequence(s)
      AF259078
      UniProtKB/Swiss-Prot
      Q9N0P9
      Conserved Domains (1) summary
      cd14100
      Location:37 → 290
      STKc_PIM1; Catalytic domain of the Serine/Threonine kinase, Proviral Integration Moloney virus (PIM) kinase 1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      11066555..11071948
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N0P9.1 GenPept UniProtKB/Swiss-Prot:Q9N0P9

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