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    RNASE6 ribonuclease A family member k6 [ Bos taurus (domestic cattle) ]

    Gene ID: 282341, updated on 28-Dec-2024

    Summary

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    Official Symbol
    RNASE6provided by VGNC
    Official Full Name
    ribonuclease A family member k6provided by VGNC
    Primary source
    VGNC:VGNC:33999
    See related
    BGD:BT11567; Ensembl:ENSBTAG00000008792
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RNASE6 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (26370330..26371958, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346352 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene ribonuclease, RNase A family, 1 (pancreatic) Neighboring gene uncharacterized LOC132346353 Neighboring gene epididymal secretory protein E3-beta pseudogene Neighboring gene ribonuclease A family member 4 Neighboring gene angiogenin, ribonuclease, RNase A family, 5 Neighboring gene angiogenin 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Complete cDNA sequence and amino acid analysis of a bovine ribonuclease K6 gene. Pietrowski D, et al. DNA Seq, 2000. PMID 11092753
    2. Complete cDNA sequence and amino acid analysis of a bovine ribonuclease K6 gene. Pietrowski D, et al. DNA Seq, 2000. PMID 10902921
    3. Primary structure of a non-secretory ribonuclease from bovine kidney. Irie M, et al. J Biochem, 1988 Aug. PMID 3182769
    4. Molecular cloning and characterization of a novel human ribonuclease (RNase k6): increasing diversity in the enlarging ribonuclease gene family. Rosenberg HF, et al. Nucleic Acids Res, 1996 Sep 15. PMID 8836175, Free PMC Article
    5. Purification and properties of bovine kidney ribonucleases. Niwata Y, et al. J Biochem, 1985 Mar. PMID 3926759

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC133715

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antibacterial humoral response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-negative bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribonuclease K6
    Names
    K6b
    RNase K2
    RNase K6
    ribonuclease K2
    ribonuclease, RNase A family, k6
    NP_777019.1
    XP_010807378.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174594.2 → NP_777019.1  ribonuclease K6 precursor

      Status: PROVISIONAL

      Source sequence(s)
      AF164025
      UniProtKB/Swiss-Prot
      P08904, Q32L16, Q95324, Q9TUP9
      Related
      ENSBTAP00000080624.1, ENSBTAT00000110398.1
      Conserved Domains (1) summary
      pfam00074
      Location:35 → 151
      RnaseA; Pancreatic ribonuclease

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      26370330..26371958 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010809076.3 → XP_010807378.1  ribonuclease K6 isoform X1

      UniProtKB/Swiss-Prot
      P08904, Q32L16, Q95324, Q9TUP9
      Related
      ENSBTAP00000011585.3, ENSBTAT00000011585.5
      Conserved Domains (1) summary
      pfam00074
      Location:35 → 151
      RnaseA; Pancreatic ribonuclease
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P08904.3 GenPept UniProtKB/Swiss-Prot:P08904

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