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    CG6424 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37012, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6424provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028494
    Locus tag
    Dmel_CG6424
    See related
    AllianceGenome:FB:FBgn0028494
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.96; anon-WO0153538.32; anon-WO0153538.33; anon-WO0153538.34; BcDNA:GH05095; Dmel\CG6424; GH05095
    Summary
    Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to several human genes including FAM13B (family with sequence similarity 13 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6424 in Genome Data Viewer
    Location:
    54E1-54E1; 2-84 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17703335..17719346, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13590840..13606851, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U snoRNA host gene 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dachs ligand with SH3s Neighboring gene Sorting nexin 16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila. DeSalvo MK, et al. Glia, 2011 Sep. PMID 21351158, Free PMC Article
    2. Proper splicing contributes to visual function in the aging Drosophila eye. Stegeman R, et al. Aging Cell, 2018 Oct. PMID 30003673, Free PMC Article
    3. Using the P[wHy] hybrid transposable element to disrupt genes in region 54D-55B in Drosophila melanogaster. Mohr SE, et al. Genetics, 2002 Sep. PMID 12242231, Free PMC Article
    4. Extensive identification and analysis of conserved small ORFs in animals. Mackowiak SD, et al. Genome Biol, 2015 Sep 14. PMID 26364619, Free PMC Article
    5. Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes. Takahashi H, et al. Sci Rep, 2020 Oct 1. PMID 33004976, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6424-PA
    CG6424-PB
    CG6424-PC
    CG6424-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17703335..17719346 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166246.3 → NP_725709.1  uncharacterized protein Dmel_CG6424, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725709.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E938, T2GGE1
      Related
      FBpp0086046
      Conserved Domains (1) summary
      PRK02224
      Location:462 → 626
      PRK02224; chromosome segregation protein; Provisional

    2. NM_001299617.1 → NP_001286546.1  uncharacterized protein Dmel_CG6424, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286546.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E938, T2GGE1
      Conserved Domains (1) summary
      PRK02224
      Location:462 → 626
      PRK02224; chromosome segregation protein; Provisional

    3. NM_137405.4 → NP_611249.2  uncharacterized protein Dmel_CG6424, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611249.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E938, T2GGE1
      Related
      FBpp0086047
      Conserved Domains (1) summary
      PRK02224
      Location:462 → 626
      PRK02224; chromosome segregation protein; Provisional

    4. NM_001169710.2 → NP_001163181.1  uncharacterized protein Dmel_CG6424, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163181.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E938, T2GGE1
      Conserved Domains (1) summary
      PRK02224
      Location:462 → 626
      PRK02224; chromosome segregation protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E938 Q0E938
    Q9U4H1 Q9U4H1

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