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    Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287429, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Naa38provided by RGD
    Official Full Name
    N(alpha)-acetyltransferase 38, NatC auxiliary subunitprovided by RGD
    Primary source
    RGD:1559617
    See related
    EnsemblRapid:ENSRNOG00000090113 AllianceGenome:RGD:1559617
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lsmd1; RGD1559617
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of NatC complex. Orthologous to human NAA38 (N-alpha-acetyltransferase 38, NatC auxiliary subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 177.1), Heart (RPKM 175.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Naa38 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (54588304..54617715)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54117754..54118913)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (55997614..55998691)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 227 Neighboring gene small Cajal body-specific RNA 21 Neighboring gene chromodomain helicase DNA binding protein 3 Neighboring gene cytochrome b5 domain containing 1 Neighboring gene transmembrane protein 88 Neighboring gene lysine demethylase 6B Neighboring gene dynein, axonemal, heavy chain 2 Neighboring gene uncharacterized LOC102557224

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization. Starheim KK, et al. Mol Cell Biol, 2009 Jul. PMID 19398576, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of NatC complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    N(alpha)-acetyltransferase 38, NatC auxiliary subunit
    Names
    LSM domain-containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105794.3 → NP_001099264.2  N(alpha)-acetyltransferase 38, NatC auxiliary subunit

      See identical proteins and their annotated locations for NP_001099264.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HFQ6
      Conserved Domains (1) summary
      cd06168
      Location:42 → 115
      LSMD1; LSM domain containing 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      54588304..54617715
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085444.2 → XP_038941372.1  N(alpha)-acetyltransferase 38, NatC auxiliary subunit isoform X1

      UniProtKB/TrEMBL
      G3V785
      Related
      ENSRNOP00000100970.1, ENSRNOT00000167755.1

    2. XM_063268637.1 → XP_063124707.1  N(alpha)-acetyltransferase 38, NatC auxiliary subunit isoform X2

      UniProtKB/TrEMBL
      A6HFQ6
    Nucleotide Protein Strain
    Heading Accession and Version

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