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    RAP1B RAP1B, member of RAS oncogene family [ Bos taurus (domestic cattle) ]

    Gene ID: 327708, updated on 3-Dec-2024

    Summary

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    Gene symbol
    RAP1B
    Gene description
    RAP1B, member of RAS oncogene family
    See related
    BGD:BT11248; Ensembl:ENSBTAG00000008967
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RAP1B in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (45156905..45200871, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104972426 Neighboring gene solute carrier family 35 member E3 Neighboring gene small nucleolar RNA SNORA38 Neighboring gene nucleoporin 107 Neighboring gene uncharacterized LOC104972428 Neighboring gene uncharacterized LOC132345284

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine. Kawata M, et al. Proc Natl Acad Sci U S A, 1990 Nov. PMID 2123345, Free PMC Article
    2. Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B. Matsui Y, et al. Biochem Biophys Res Commun, 1990 Jan 30. PMID 2105724
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GDP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rap protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to cAMP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of synaptic vesicle exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras-related protein Rap-1b
    Names
    GTP-binding protein smg p21B
    NP_787018.1
    XP_005206506.1
    XP_010803386.1
    XP_024847169.1
    XP_059742119.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175824.2 → NP_787018.1  ras-related protein Rap-1b

      See identical proteins and their annotated locations for NP_787018.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102330
      UniProtKB/Swiss-Prot
      P61223, Q3T0M4
      UniProtKB/TrEMBL
      A0AAF6Z0F2
      Related
      ENSBTAP00000011803.3, ENSBTAT00000011803.4
      Conserved Domains (1) summary
      cd04175
      Location:3 → 167
      Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      45156905..45200871 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010805084.4 → XP_010803386.1  ras-related protein Rap-1b isoform X1

      See identical proteins and their annotated locations for XP_010803386.1

      UniProtKB/Swiss-Prot
      P61223, Q3T0M4
      UniProtKB/TrEMBL
      A0AAF6Z0F2
      Conserved Domains (1) summary
      cd04175
      Location:3 → 167
      Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

    2. XM_059886136.1 → XP_059742119.1  ras-related protein Rap-1b isoform X1

      UniProtKB/Swiss-Prot
      P61223, Q3T0M4
      UniProtKB/TrEMBL
      A0AAF6Z0F2

    3. XM_005206449.5 → XP_005206506.1  ras-related protein Rap-1b isoform X1

      See identical proteins and their annotated locations for XP_005206506.1

      UniProtKB/Swiss-Prot
      P61223, Q3T0M4
      UniProtKB/TrEMBL
      A0AAF6Z0F2
      Conserved Domains (1) summary
      cd04175
      Location:3 → 167
      Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

    4. XM_024991401.2 → XP_024847169.1  ras-related protein Rap-1b isoform X1

      UniProtKB/Swiss-Prot
      P61223, Q3T0M4
      UniProtKB/TrEMBL
      A0AAF6Z0F2
      Conserved Domains (1) summary
      cd04175
      Location:3 → 167
      Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P61223.1 GenPept UniProtKB/Swiss-Prot:P61223

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