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    KLLA0_D04906g 3-isopropylmalate dehydrogenase [ Kluyveromyces lactis ]

    Gene ID: 2892896, updated on 6-Dec-2024

    Summary

    Gene symbol
    KLLA0_D04906g
    Gene description
    3-isopropylmalate dehydrogenase
    Locus tag
    KLLA0_D04906g
    See related
    FungiDB:KLLA0_D04906g; VEuPathDB:KLLA0_D04906g
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Kluyveromyces lactis (strain: NRRL Y-1140)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces
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    Genomic context

    See KLLA0_D04906g in Genome Data Viewer
    Location:
    chromosome: D
    Exon count:
    1
    Sequence:
    Chromosome: D; NC_006040.1 (420903..421991)

    Chromosome D - NC_006040.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene cysteine desulfurase Neighboring gene uncharacterized protein

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3-isopropylmalate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in L-leucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    3-isopropylmalate dehydrogenase
    XP_453278.1
    • highly similar to uniprot|P04173 Saccharomyces cerevisiae YCL018W LEU2 Beta-isopropylmalate dehydrogenase catalyzes the third step in the leucine biosynthesis pathway

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_006040.1 Reference assembly

      Range
      420903..421991
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_453278.1XP_453278.1  3-isopropylmalate dehydrogenase [Kluyveromyces lactis]

      See identical proteins and their annotated locations for XP_453278.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P23390
      Conserved Domains (1) summary
      cl00445
      Location:4352
      Iso_dh; Isocitrate/isopropylmalate dehydrogenase