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    tinc tincar [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42148, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tincprovided by FlyBase
    Official Full Name
    tincarprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261649
    Locus tag
    Dmel_CG31247
    See related
    AllianceGenome:FB:FBgn0261649
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14319; CG14320; CG31246; CG31247; CG7723; Dmel\CG31247
    Old locus tag
    Dmel_CG31246
    Summary
    Involved in regulation of eye photoreceptor cell development. Is expressed in adult head; anlage in statu nascendi; organism; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See tinc in Genome Data Viewer
    Location:
    90C6-90C8; 3-61 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17811541..17872507)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13637263..13698229)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Oddjob Neighboring gene ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase Neighboring gene Rab3 interacting molecule Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster. Hirota Y, et al. Dev Genes Evol, 2005 Feb. PMID 15654626
    2. tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila. Hirota Y, et al. Mech Dev, 2002 Dec. PMID 14516698
    3. An amino acid polymorphism in the couch potato gene forms the basis for climatic adaptation in Drosophila melanogaster. Schmidt PS, et al. Proc Natl Acad Sci U S A, 2008 Oct 21. PMID 18852464, Free PMC Article
    4. Conditional switches for extracellular matrix patterning in Drosophila melanogaster. Khokhar A, et al. Genetics, 2008 Mar. PMID 18245854, Free PMC Article
    5. An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila. Tsuda L, et al. EMBO J, 2006 Jul 12. PMID 16763555, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Tinc has an indispensable role in the normal differentiation of ommatidial cells.
      Title: The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 17837845-17837990 mobile_element_type = transposon:INE-1{}4763

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of eye photoreceptor cell development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tincar
    Names
    CG31247-PA
    CG31247-PB
    CG31247-PE
    CG31247-PF
    CG31247-PG
    tinc-PA
    tinc-PB
    tinc-PE
    tinc-PF
    tinc-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      17811541..17872507
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176509.4 → NP_788686.1  tincar, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788686.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V318, Q1EBX7, Q1EBX9, Q6NP49, Q86B90, Q86B91, Q8MUW7, Q8MZ15, Q9VEE7
      UniProtKB/TrEMBL
      A0A0B4KGD5
      Related
      FBpp0088712

    2. NM_169780.5 → NP_732278.2  tincar, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732278.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B91
      Related
      FBpp0088713

    3. NM_176511.3 → NP_788688.2  tincar, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788688.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V318, Q1EBX7, Q1EBX9, Q6NP49, Q86B90, Q86B91, Q8MUW7, Q8MZ15, Q9VEE7
      UniProtKB/TrEMBL
      A0A0B4KGD5

    4. NM_001275757.1 → NP_001262686.1  tincar, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262686.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V318, Q1EBX7, Q1EBX9, Q6NP49, Q86B90, Q86B91, Q8MUW7, Q8MZ15, Q9VEE7
      UniProtKB/TrEMBL
      A0A0B4KGD5

    5. NM_176510.5 → NP_788687.3  tincar, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788687.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V318, Q1EBX7, Q1EBX9, Q6NP49, Q86B90, Q86B91, Q8MUW7, Q8MZ15, Q9VEE7
      UniProtKB/TrEMBL
      A0A0B4KGD5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGD5 A0A0B4KGD5
    Q86B91.1 Q86B91

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