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    Gm10499 predicted gene 10499 [ Mus musculus (house mouse) ]

    Gene ID: 69717, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Gm10499provided by MGI
    Official Full Name
    predicted gene 10499provided by MGI
    Primary source
    MGI:MGI:3702919
    See related
    Ensembl:ENSMUSG00000121510
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H-2T7; H2-T7; MumuTL
    Expression
    Biased expression in duodenum adult (RPKM 75.2), small intestine adult (RPKM 55.2) and 9 other tissues See more
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    Genomic context

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    See Gm10499 in Genome Data Viewer
    Location:
    17 B1; 17 18.95 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36452640..36457092, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (36141748..36146200, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene histocompatibility-2, T region locus 25 Neighboring gene histocompatibility 2, T region pseudogene Neighboring gene RIKEN cDNA 2410017I17 gene Neighboring gene histocompatibility 2, T region locus 26 Neighboring gene akirin 1 pseudogene Neighboring gene akirin 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6. Ohtsuka M, et al. BMC Genomics, 2008 Apr 17. PMID 18416856, Free PMC Article
    2. Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse. Weiss EH, et al. Nature, 1984 Aug 23-29. PMID 6088985
    3. A physical map of the Q region of B1O.P. Litaker W, et al. Mamm Genome, 1996 Mar. PMID 8833240
    4. Clusters of genes encoding mouse transplantation antigens. Steinmetz M, et al. Cell, 1982 Mar. PMID 6280871
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    gene 10499
    Names
    MHC class I antigen
    histocompatibility 2, T region locus 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370818.1 → NP_001357747.1  gene 10499 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AI605939, CD541295, CT030728
      Related
      ENSMUST00000292570.1
      Conserved Domains (2) summary
      cd07698
      Location:204 → 296
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:23 → 200
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    2. NM_001370819.1 → NP_001357748.1  gene 10499 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AI605939, CD541295, CT030728
      Conserved Domains (2) summary
      cd07698
      Location:204 → 296
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:23 → 200
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    3. NM_001370820.1 → NP_001357749.1  gene 10499 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AI605939, CD541295, CT030728
      Conserved Domains (3) summary
      cd07698
      Location:204 → 295
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:23 → 200
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
      pfam06623
      Location:296 → 320
      MHC_I_C; MHC_I C-terminus

    4. NM_001370821.1 → NP_001357750.1  gene 10499 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AI605939, CD541295, CT030728
      Conserved Domains (2) summary
      cd07698
      Location:204 → 295
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:23 → 200
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      36452640..36457092 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317765.2 → XP_017173254.1  gene 10499 isoform X1

      Related
      ENSMUST00000292569.1
      Conserved Domains (3) summary
      cd07698
      Location:212 → 304
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:31 → 208
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
      pfam06623
      Location:346 → 370
      MHC_I_C; MHC_I C-terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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