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    C55A6.10 Macro domain-containing protein;NARG2_C domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179581, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C55A6.10
    Official Full Name
    Macro domain-containing protein;NARG2_C domain-containing protein
    Primary source
    WormBase:WBGene00008339
    Locus tag
    CELE_C55A6.10
    See related
    AllianceGenome:WB:WBGene00008339
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in striated muscle dense body. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 66. Orthologous to human FERRY3 (FERRY endosomal RAB5 effector complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C55A6.10 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (11505347..11508271)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene THAP4-like heme-binding beta-barrel domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene E3 ubiquitin-protein ligase Neighboring gene ncRNA Neighboring gene Tubulin polyglutamylase ttll-5 Neighboring gene DeHydrogenases, Short chain Neighboring gene DeHydrogenases, Short chain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in striated muscle dense body HDA PubMed 

    General protein information

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    Preferred Names
    Macro domain-containing protein;NARG2_C domain-containing protein
    NP_001256329.1
    • Confirmed by transcript evidence
    NP_001256330.1
    • Confirmed by transcript evidence
    NP_001360533.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11505347..11508271
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373111.2 → NP_001360533.1  NARG2_C domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WVH5
      Conserved Domains (1) summary
      pfam10154
      Location:49 → 547
      DUF2362; Uncharacterized conserved protein (DUF2362)

    2. NM_001269400.4 → NP_001256329.1  NARG2_C domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256329.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8WQF9
      Conserved Domains (1) summary
      pfam10154
      Location:49 → 545
      DUF2362; Uncharacterized conserved protein (DUF2362)

    3. NM_001269401.3 → NP_001256330.1  Macro domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256330.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E9P885
      Conserved Domains (1) summary
      pfam10154
      Location:1 → 267
      DUF2362; Uncharacterized conserved protein (DUF2362)
    Nucleotide Protein
    Heading Accession and Version

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