Lectin-galC1 Galactose-specific C-type lectin [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Lectin-galC1provided by FlyBase
Official Full Name: Galactose-specific C-type lectinprovided by FlyBase
Primary source: FLYBASE:FBgn0016675
Locus tag: Dmel_CG9976
See related: AllianceGenome:FB:FBgn0016675
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: AC007082a; CG9976; Dgal-1; DL1; Dmel\CG9976; Lecti-galC1; lectin Gal-C; lectin-galC1; LGC1
Summary: Enables galactose binding activity. Involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules and induction of bacterial agglutination. Located in extracellular region. Is expressed in several structures, including cuticle; embryonic/larval fat body; gonad; imaginal disc; and somatic muscle cell. Orthologous to human CLEC6A (C-type lectin domain containing 6A); CLEC4D (C-type lectin domain family 4 member D); and CLEC4E (C-type lectin domain family 4 member E). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (19417447..19418274)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (19417447..19418274)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables carbohydrate binding	IBA Inferred from Biological aspect of Ancestor more info
enables galactose binding	IDA Inferred from Direct Assay more info	PubMed
enables pattern recognition receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IDA Inferred from Direct Assay more info	PubMed
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info
involved_in induction of bacterial agglutination	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular region	ISM Inferred from Sequence Model more info	PubMed

Names: CG9976-PA; CG9976-PB; Lectin-galC1-PA; Lectin-galC1-PB; drosophila lectin 1; galactin; galactose specific C-type lectin; lectin; lectin-galC1

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The following sections contain reference sequences that belong to a specific genome build. Explain