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    F25D1.3 Interleukin-17 [ Caenorhabditis elegans ]

    Gene ID: 179468, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F25D1.3
    Official Full Name
    Interleukin-17
    Primary source
    WormBase:WBGene00009108
    Locus tag
    CELE_F25D1.3
    See related
    AllianceGenome:WB:WBGene00009108
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cytokine activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including Mycobacterium avium complex disease; autoimmune disease (multiple); bronchial disease (multiple); chronic mucocutaneous candidiasis; and rhinitis (multiple). Orthologous to human IL17A (interleukin 17A); IL17C (interleukin 17C); and IL17F (interleukin 17F). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F25D1.3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (10528724..10530636)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Exportin-7 Neighboring gene Histone deacetylase domain-containing protein Neighboring gene MFS transporter Neighboring gene Protein phosphatase ppm-1.A Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Interleukin-17
    NP_505700.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10528724..10530636
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073299.6 → NP_505700.2  Interleukin-17 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505700.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDD7
      Conserved Domains (1) summary
      pfam06083
      Location:93 → 169
      IL17; Interleukin-17
    Nucleotide Protein
    Heading Accession and Version

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