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    oma-2 CCCH-type zinc finger protein oma-2 [ Caenorhabditis elegans ]

    Gene ID: 179183, updated on 9-Dec-2024

    Summary

    Official Symbol
    oma-2
    Official Full Name
    CCCH-type zinc finger protein oma-2
    Primary source
    WormBase:WBGene00003865
    Locus tag
    CELE_ZC513.6
    See related
    AllianceGenome:WB:WBGene00003865
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables mRNA regulatory element binding translation repressor activity. Involved in several processes, including oocyte development; regulation of cell development; and regulation of protein metabolic process. Located in P granule and centrosome. Is expressed in several structures, including AB; germ line; head muscle; oocyte; and somatic nervous system. Orthologous to human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See oma-2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (8029439..8031214)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Glycine N-acyltransferase-like protein Neighboring gene valine--tRNA ligase Neighboring gene DUF19 domain-containing protein Neighboring gene Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA regulatory element binding translation repressor activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in establishment of chromosome localization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in meiotic nuclear membrane disassembly IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of meiotic cell cycle process involved in oocyte maturation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of ovulation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in oocyte growth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in oocyte maturation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in oocyte morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of MAP kinase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of embryonic development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of fertilization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of meiotic cell cycle process involved in oocyte maturation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of oocyte development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of oocyte maturation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in protein localization to chromatin IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in P granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    CCCH-type zinc finger protein oma-2
    NP_505069.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8029439..8031214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072668.9NP_505069.1  CCCH-type zinc finger protein oma-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505069.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q23359
      Conserved Domains (1) summary
      cl11592
      Location:10172
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)