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    LINC01121 long intergenic non-protein coding RNA 1121 [ Homo sapiens (human) ]

    Gene ID: 400952, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC01121provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1121provided by HGNC
    Primary source
    HGNC:HGNC:49266
    See related
    Ensembl:ENSG00000205054 AllianceGenome:HGNC:49266
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UNQ6975
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC01121 in Genome Data Viewer
    Location:
    2p21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (45174341..45254941, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (45179561..45260151, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (45401480..45482080, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45232925-45233468 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45233469-45234012 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45235286-45236059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45237064-45237663 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45239927-45240747 Neighboring gene NANOG hESC enhancer GRCh37_chr2:45261729-45262230 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:45266703-45267902 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45291852-45292470 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45298897-45299398 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45299399-45299898 Neighboring gene SIX homeobox 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45303064-45303728 Neighboring gene uncharacterized LOC107985809 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45396231-45396731 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45397597-45398226 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45417644-45418148 Neighboring gene uncharacterized LOC105374576 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45446124-45447052 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45447053-45447979 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45483718-45484291 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45484292-45484864 Neighboring gene uncharacterized LOC105374577 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45570374-45571192 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45571193-45572010 Neighboring gene Sharpr-MPRA regulatory region 15185 Neighboring gene S1 RNA binding domain 1 Neighboring gene NANOG hESC enhancer GRCh37_chr2:45693107-45693617 Neighboring gene Sharpr-MPRA regulatory region 7031 Neighboring gene RNA, 7SL, cytoplasmic 414, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis. Chen X, et al. J Gene Med, 2020 Oct. PMID 32436632
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Clark HF, et al. Genome Res, 2003 Oct. PMID 12975309, Free PMC Article
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis.
      Title: LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • NGNL6975

    Clone Names

    • FLJ38231

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_033831.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AW291903, AY358255
      Related
      ENST00000378479.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      45174341..45254941 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      45179561..45260151 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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