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    jv javelin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318008, updated on 9-Dec-2024

    Summary

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    Official Symbol
    jvprovided by FlyBase
    Official Full Name
    javelinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0263973
    Locus tag
    Dmel_CG32397
    See related
    AllianceGenome:FB:FBgn0263973
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0138581.6; CG32397; Dmel\CG32397
    Summary
    Involved in chaeta morphogenesis and parallel actin filament bundle assembly. Colocalizes with actin filament bundle. Is expressed in spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    Location:
    65B5-65B5; 3-17 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6563197..6589479, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6556297..6582579, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene sulfateless Neighboring gene long non-coding RNA:CR46500 Neighboring gene beta-Tubulin at 65B Neighboring gene Mitochondrial calcium uniporter Neighboring gene nudel Neighboring gene RNA exonuclease 5 Neighboring gene zero population growth

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Minutes: mutants of drosophila autonomously affecting cell division rate. Morata G, et al. Dev Biol, 1975 Feb. PMID 1116643
    2. Recapitulating Actin Module Organization in the Drosophila Oocyte Reveals New Roles for Bristle-Actin-Modulating Proteins. Krishnan RK, et al. Int J Mol Sci, 2021 Apr 13. PMID 33924532, Free PMC Article
    3. Cloning, structure, cellular localization, and possible function of the tumor suppressor gene lethal(3)malignant blood neoplasm-1 of Drosophila melanogaster. Konrad L, et al. Dev Biol, 1994 May. PMID 8174791
    4. Clonal analysis in hybrids between Drosophila melanogaster and Drosophila simulans. Sanchez L, et al. Rouxs Arch Dev Biol, 1994 Dec. PMID 28305934
    5. Genetic Analysis of the Hairy Locus in DROSOPHILA MELANOGASTER. Ingham PW, et al. Genetics, 1985 Nov. PMID 17246301, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the javelin gene is an allele of the predicted CG32397 gene that encodes a protein with no homologs outside insects.
      Title: The Drosophila javelin gene encodes a novel actin-associated protein required for actin assembly in the bristle.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in chaeta morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in parallel actin filament bundle assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with actin filament bundle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    javelin
    Names
    CG32397-PB
    CG32397-PC
    CG32397-PD
    jv-PB
    jv-PC
    jv-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6563197..6589479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168171.4 → NP_729175.3  javelin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729175.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9NE38
      Conserved Domains (1) summary
      PTZ00121
      Location:738 → 951
      PTZ00121; MAEBL; Provisional

    2. NM_001259720.2 → NP_001246649.1  javelin, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246649.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9NE38, Q8IQ69
      Conserved Domains (1) summary
      cl26511
      Location:758 → 971
      Neuromodulin_N; Gap junction protein N-terminal region

    3. NM_001259719.2 → NP_001246648.1  javelin, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246648.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9NE38
      Conserved Domains (1) summary
      PTZ00121
      Location:738 → 951
      PTZ00121; MAEBL; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NE38.1 M9NE38

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