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    Y41E3.8 Glycine Rich Secreted Protein [ Caenorhabditis elegans ]

    Gene ID: 178417, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y41E3.8
    Official Full Name
    Glycine Rich Secreted Protein
    Primary source
    WormBase:WBGene00012766
    Locus tag
    CELE_Y41E3.8
    See related
    AllianceGenome:WB:WBGene00012766
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. Orthologous to human SELENOK (selenoprotein K). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y41E3.8 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (15028358..15028978, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Glutaminyl-tRNA synthetase;Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding domain-containing protein;glutamine--tRNA ligase;putative glutamine--tRNA ligase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ACB domain-containing protein;GOLD domain-containing protein;Golgi resident protein GCP60 Neighboring gene FANCD2 Neighboring gene ncRNA Neighboring gene putative elongation factor 1-beta/1-delta 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    acts_upstream_of_or_within IRE1-mediated unfolded protein response HEP PubMed 
    involved_in calcium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Glycine Rich Secreted Protein
    NP_001294102.1
    • Confirmed by transcript evidence
    NP_502815.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      15028358..15028978 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070414.7 → NP_502815.1  Glycine Rich Secreted Protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502815.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62437
      Conserved Domains (1) summary
      pfam10961
      Location:2 → 54
      DUF2763; Protein of unknown function (DUF2763)

    2. NM_001307173.3 → NP_001294102.1  Glycine Rich Secreted Protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294102.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A078BTL4
      Conserved Domains (1) summary
      pfam10961
      Location:1 → 34
      DUF2763; Protein of unknown function (DUF2763)
    Nucleotide Protein
    Heading Accession and Version

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