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    apc-10 Anaphase-promoting complex subunit 10 [ Caenorhabditis elegans ]

    Gene ID: 179454, updated on 9-Dec-2024

    Summary

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    Official Symbol
    apc-10
    Official Full Name
    Anaphase-promoting complex subunit 10
    Primary source
    WormBase:WBGene00000144
    Locus tag
    CELE_F15H10.3
    See related
    AllianceGenome:WB:WBGene00000144
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein K11-linked ubiquitination. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC10 (anaphase promoting complex subunit 10). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See apc-10 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (10425362..10426353, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Cuticle collagen 13 Neighboring gene Cuticle collagen 12 Neighboring gene RING-type domain-containing protein Neighboring gene Amino acid transporter transmembrane domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of Caenorhabditis elegans phosphoproteome reveals the involvement of a molecular chaperone, HSP-90 protein during Salmonella enterica Serovar Typhi infection. Balasubramaniam B, et al. Int J Biol Macromol, 2019 Sep 15. PMID 31252012
    2. Anaphase-promoting complex in Caenorhabditis elegans. Yeong FM. Mol Cell Biol, 2004 Mar. PMID 14993261, Free PMC Article
    3. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    4. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of anaphase-promoting complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Anaphase-promoting complex subunit 10
    NP_001256217.1
    • Confirmed by transcript evidence
    NP_001256218.1
    • Confirmed by transcript evidence
    NP_001256219.1
    • Confirmed by transcript evidence
    NP_001256220.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10425362..10426353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269291.2 → NP_001256220.1  Anaphase-promoting complex subunit 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256220.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2L2B8
      Conserved Domains (1) summary
      pfam03256
      Location:2 → 185
      ANAPC10; Anaphase-promoting complex, subunit 10 (APC10)

    2. NM_001269290.3 → NP_001256219.1  Anaphase-promoting complex subunit 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256219.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2L2B8, Q19487
      Conserved Domains (1) summary
      pfam03256
      Location:13 → 196
      ANAPC10; Anaphase-promoting complex, subunit 10 (APC10)

    3. NM_001269288.3 → NP_001256217.1  Anaphase-promoting complex subunit 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256217.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2L2B8, Q19487
      Conserved Domains (1) summary
      pfam03256
      Location:13 → 196
      ANAPC10; Anaphase-promoting complex, subunit 10 (APC10)

    4. NM_001269289.4 → NP_001256218.1  Anaphase-promoting complex subunit 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256218.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2L2B8, Q19487
      Conserved Domains (1) summary
      pfam03256
      Location:13 → 196
      ANAPC10; Anaphase-promoting complex, subunit 10 (APC10)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    H2L2B8.1

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