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    GAT4 Gat4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854830, updated on 9-Dec-2024

    Summary

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    Official Symbol
    GAT4
    Official Full Name
    Gat4p
    Primary source
    SGD:S000001452
    Locus tag
    YIR013C
    See related
    AllianceGenome:SGD:S000001452; FungiDB:YIR013C; VEuPathDB:YIR013C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Involved in cellular response to zinc ion starvation and positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See GAT4 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (380019..380384, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Sts1p Neighboring gene Sqt1p Neighboring gene Vld1p Neighboring gene ribonuclease P protein subunit RPR2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide transcriptional analysis in S. cerevisiae by mini-array membrane hybridization. Cox KH, et al. Yeast, 1999 Jun 15. PMID 10392447
    2. Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast. Jin L, et al. Mol Cell Biol, 2015 Oct. PMID 26217015, Free PMC Article
    3. A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae. Lin CP, et al. PLoS Genet, 2013. PMID 23966878, Free PMC Article
    4. Massively parallel measurements of molecular interaction kinetics on a microfluidic platform. Geertz M, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012409, Free PMC Article
    5. High-resolution DNA-binding specificity analysis of yeast transcription factors. Zhu C, et al. Genome Res, 2009 Apr. PMID 19158363, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to zinc ion starvation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Gat4p
    NP_012278.3
    • Protein containing GATA family zinc finger motifs; involved in spore wall assembly; sequence similarity to GAT3, and the double mutant gat3 gat4 exhibits reduced dityrosine fluorescence relative to the single mutants

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      380019..380384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179535.3 → NP_012278.3  TPA: Gat4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012278.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVU3, P40569
      UniProtKB/TrEMBL
      A6ZVT2, B3LTJ6, C7GJF9, C8ZAR2, G2WGF9, N1P1S4
      Conserved Domains (1) summary
      cd00202
      Location:52 → 108
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40569.1

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