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    HAB1 Hab1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852588, updated on 9-Dec-2024

    Summary

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    Official Symbol
    HAB1
    Official Full Name
    Hab1p
    Primary source
    SGD:S000000489
    Locus tag
    YBR285W
    See related
    AllianceGenome:SGD:S000000489; FungiDB:YBR285W; VEuPathDB:YBR285W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables ribosome binding activity. Involved in autophagy. Is active in autophagosome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See HAB1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (773922..774356)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Ssh1p Neighboring gene metallo-dependent hydrolase superfamily protein Neighboring gene aminopeptidase Y Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Generation of null alleles for the functional analysis of six genes from the right arm of Saccharomyces cerevisiae chromosome II. Dueñas E, et al. Yeast, 1999 May. PMID 10341424
    2. Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening. Mah AS, et al. BMC Biochem, 2005 Oct 21. PMID 16242037, Free PMC Article
    3. Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor. Fong CS, et al. FEMS Yeast Res, 2008 May. PMID 18205808
    4. Receptor-mediated cargo hitchhiking on bulk autophagy. Takeda E, et al. EMBO J, 2024 Aug. PMID 38755257, Free PMC Article
    5. Heterozygous yeast deletion collection screens reveal essential targets of Hsp90. Franzosa EA, et al. PLoS One, 2011. PMID 22140548, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ribosome binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in autophagosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Hab1p
    NP_009844.4
    • Autophagy receptor; highly enriched in autophagic body fractions of both rapamycin-treated and nitrogen-starved cells; binds directly to forming isolation membranes during bulk autophagy; small protein of 144 amino acid residues without any identifiable membrane-spanning regions; N-terminal 42 amino acid region contains an amphipathic helix and an Atg8-family interacting motif

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      773922..774356
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178633.4 → NP_009844.4  TPA: Hab1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009844.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQT0, P38354, P89508, Q6B2Z4
      UniProtKB/TrEMBL
      A6ZLM3, B3LMM8, C7GMU7, D3UF32, G2W9T8, N1P8W2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38354.2

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