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    Alyreffm11 Aly/REF export factor family member 11 [ Mus musculus (house mouse) ]

    Gene ID: 100861880, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Alyreffm11provided by MGI
    Official Full Name
    Aly/REF export factor family member 11provided by MGI
    Primary source
    MGI:MGI:5434648
    See related
    Ensembl:ENSMUSG00000091779 AllianceGenome:MGI:5434648
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm21293
    Summary
    Predicted to enable C5-methylcytidine-containing RNA reader activity and mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in cytoplasm. Predicted to be part of catalytic step 2 spliceosome; exon-exon junction complex; and transcription export complex. Predicted to be active in nucleus. Predicted to colocalize with chromosome, telomeric region. Orthologous to human ALYREF (Aly/REF export factor). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Alyreffm11 in Genome Data Viewer
    Location:
    10 D1; 10
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (103978848..103981288)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (104142987..104145427)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L7A pseudogene Neighboring gene STARR-seq mESC enhancer starr_27753 Neighboring gene STARR-seq mESC enhancer starr_27754 Neighboring gene predicted gene, 25143 Neighboring gene Aly/REF export factor family member 14 Neighboring gene Aly/REF export factor family member 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables C5-methylcytidine-containing RNA reader activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in mRNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    colocalizes_with chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of exon-exon junction complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of transcription export complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RNA and export factor-binding protein 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001270898.1 → NP_001257827.1  RNA and export factor-binding protein 2-like

      See identical proteins and their annotated locations for NP_001257827.1

      Status: VALIDATED

      Source sequence(s)
      AC192091
      UniProtKB/TrEMBL
      M0QWB2, M0QWR4
      Related
      ENSMUSP00000137742.2, ENSMUST00000181634.8
      Conserved Domains (3) summary
      COG0724
      Location:79 → 186
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12680
      Location:86 → 160
      RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins
      pfam07078
      Location:6 → 59
      FYTT; Forty-two-three protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      103978848..103981288
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017313753.1 → XP_017169242.1  RNA and export factor-binding protein 2-like isoform X1

      UniProtKB/TrEMBL
      M0QWB2, M0QWR4
      Conserved Domains (3) summary
      cd12680
      Location:86 → 160
      RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins
      TIGR01648
      Location:26 → 179
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family
      pfam13865
      Location:169 → 230
      FoP_duplication; C-terminal duplication domain of Friend of PRMT1

    2. XM_030244792.1 → XP_030100652.1  RNA and export factor-binding protein 2-like isoform X2

      UniProtKB/TrEMBL
      M0QWB2, M0QWR4
      Conserved Domains (3) summary
      cd12680
      Location:86 → 160
      RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins
      TIGR01648
      Location:26 → 179
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family
      pfam13865
      Location:169 → 229
      FoP_duplication; C-terminal duplication domain of Friend of PRMT1
    Nucleotide Protein
    Heading Accession and Version

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