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    KAFR0L02060 hydroxymethylglutaryl-CoA synthase [ Kazachstania africana CBS 2517 ]

    Gene ID: 13887024, updated on 6-Dec-2024

    Summary

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    Gene symbol
    KAFR0L02060
    Gene description
    hydroxymethylglutaryl-CoA synthase
    Locus tag
    KAFR_0L02060
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Kazachstania africana CBS 2517 (strain: type strain:CBS 2517)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kazachstania
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    Genomic context

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    See KAFR0L02060 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    1
    Sequence:
    Chromosome: 12; NC_018951.1 (389308..390693)

    Chromosome 12 - NC_018951.1Genomic Context describing neighboring genes Neighboring gene cytochrome-b5 reductase Neighboring gene SCF ubiquitin ligase complex subunit UFO1 Neighboring gene ribonuclease P Neighboring gene proteasome core particle subunit alpha 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_018951.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary erosion of yeast sex chromosomes by mating-type switching accidents. Gordon JL, et al. Proc Natl Acad Sci U S A, 2011 Dec 13. PMID 22123960, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hydroxymethylglutaryl-CoA synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ergosterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydroxymethylglutaryl-CoA synthase
    XP_003959952.1
    • similar to Saccharomyces cerevisiae ERG13 (YML126C); ancestral locus Anc_8.864

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_018951.1 Reference assembly

      Range
      389308..390693
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003959903.1 → XP_003959952.1  hydroxymethylglutaryl-CoA synthase [Kazachstania africana CBS 2517]

      See identical proteins and their annotated locations for XP_003959952.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      H2B2G7
      Conserved Domains (3) summary
      TIGR01833
      Location:15 → 460
      HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
      pfam08540
      Location:187 → 460
      HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal
      cl09938
      Location:18 → 186
      cond_enzymes; Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the ...
    Nucleotide Protein
    Heading Accession and Version

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