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    TP73 tumor protein p73 [ Pteropus alecto (black flying fox) ]

    Gene ID: 102895499, updated on 30-Mar-2024

    Summary

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    Gene symbol
    TP73
    Gene description
    tumor protein p73
    Locus tag
    PAL_GLEAN10013120
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pteropus alecto
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
    Orthologs
    human mouse all
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    Genomic context

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    See TP73 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    102 current ASM32557v1 (GCF_000325575.1) Unplaced Scaffold NW_006436888.1 (10187834..10205772, complement)

    NW_006436888.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 1 (Vel blood group) Neighboring gene coiled-coil domain containing 27 Neighboring gene WD repeat containing, antisense to TP73 Neighboring gene tumor protein p63 regulated 1 like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_006436888 Unplaced Scaffold Reference ASM32557v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein tetramerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tumor protein p73

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Pteropus alecto Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM32557v1 Primary Assembly

    Genomic

    1. NW_006436888.1 Reference ASM32557v1 Primary Assembly

      Range
      10187834..10205772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025048590.1 → XP_024904358.1  tumor protein p73 isoform X3

      Conserved Domains (3) summary
      pfam00870
      Location:42 → 238
      P53; P53 DNA-binding domain
      pfam07710
      Location:275 → 313
      P53_tetramer; P53 tetramerisation motif
      cl15755
      Location:329 → 384
      SAM_superfamily; SAM (Sterile alpha motif )

    2. XM_025048589.1 → XP_024904357.1  tumor protein p73 isoform X2

      Conserved Domains (3) summary
      pfam00870
      Location:42 → 238
      P53; P53 DNA-binding domain
      pfam07710
      Location:275 → 313
      P53_tetramer; P53 tetramerisation motif
      cl15755
      Location:374 → 399
      SAM_superfamily; SAM (Sterile alpha motif )

    3. XM_015591327.1 → XP_015446813.1  tumor protein p73 isoform X1

      UniProtKB/TrEMBL
      L5KJ90
      Conserved Domains (4) summary
      cd09571
      Location:412 → 476
      SAM_tumor-p73; SAM domain of tumor-p73 proteins
      smart00454
      Location:416 → 475
      SAM; Sterile alpha motif
      pfam00870
      Location:42 → 238
      P53; P53 DNA-binding domain
      pfam07710
      Location:274 → 313
      P53_tetramer; P53 tetramerization motif
    Nucleotide Protein
    Heading Accession and Version

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