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    Cipc Clock interacting protein circadian [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43177, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cipcprovided by FlyBase
    Official Full Name
    Clock interacting protein circadianprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051324
    Locus tag
    Dmel_CG31324
    See related
    AllianceGenome:FB:FBgn0051324
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH68619; CG14555; CG14557; CG31324; Dmel\CG31324
    Summary
    Involved in negative regulation of DNA-templated transcription and negative regulation of circadian rhythm. Is expressed in embryonic brain; embryonic/larval crystal cell; embryonic/larval midgut; and larval ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cipc in Genome Data Viewer
    Location:
    96F14-97A1; 3-90 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26106868..26130674)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21932590..21956396)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44950 Neighboring gene dysfusion Neighboring gene long non-coding RNA:CR44319 Neighboring gene long non-coding RNA:CR46060 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive tissue-specific expression variation and novel regulators underlying circadian behavior. Litovchenko M, et al. Sci Adv, 2021 Jan. PMID 33514540, Free PMC Article
    2. CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN. Rivas GBS, et al. Curr Biol, 2021 Oct 11. PMID 34331859, Free PMC Article
    3. Microarray analysis of juvenile hormone response in Drosophila melanogaster S2 cells. Willis DK, et al. J Insect Sci, 2010. PMID 20672983, Free PMC Article
    4. Divergence in Transcriptional and Regulatory Responses to Mating in Male and Female Fruitflies. Fowler EK, et al. Sci Rep, 2019 Nov 6. PMID 31695054, Free PMC Article
    5. Identification of transcriptional responsive genes to acetic acid, ethanol, and 2-phenylethanol exposure in Drosophila melanogaster. Seong KM, et al. Pestic Biochem Physiol, 2020 May. PMID 32359537

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 26108880-26117406 mobile_element_type = transposon:Tirant{}1423

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    clock interacting protein circadian
    Names
    CG31324-PA
    CG31324-PB
    CG31324-PC
    Cipc-PA
    Cipc-PB
    Cipc-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26106868..26130674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276054.1 → NP_001262983.1  clock interacting protein circadian, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262983.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95R29

    2. NM_170259.4 → NP_733138.1  clock interacting protein circadian, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733138.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95R29
      Related
      FBpp0084358

    3. NM_001276055.1 → NP_001262984.1  clock interacting protein circadian, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262984.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHX8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KHX8 A0A0B4KHX8
    Q95R29 Q95R29

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