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    Ada3 transcriptional Adaptor 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32787, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ada3provided by FlyBase
    Official Full Name
    transcriptional Adaptor 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0030891
    Locus tag
    Dmel_CG7098
    See related
    AllianceGenome:FB:FBgn0030891
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ada3; ADA3; CG7098; dAda3; dADA3; DADA3; dik; Dmel\CG7098; HL-XIV
    Summary
    Enables chromatin binding activity. Involved in transcription initiation-coupled chromatin remodeling. Located in nucleus and polytene chromosome puff. Part of ATAC complex; H3 histone acetyltransferase complex; and SAGA complex. Colocalizes with euchromatin. Is expressed in several structures, including central brain primordium; embryonic central brain neurons; embryonic/larval midgut primordium; ganglia; and germline cell. Orthologous to human TADA3 (transcriptional adaptor 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Ada3 in Genome Data Viewer
    Location:
    16F6-16F6; 1-59 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18085761..18088418)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17979794..17982451)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Shaker Neighboring gene uncharacterized protein Neighboring gene Dynein heavy chain at 16F Neighboring gene uncharacterized protein Neighboring gene Swt1 RNA endoribonuclease Neighboring gene scully

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription initiation-coupled chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of ATAC complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of H3 histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of SAGA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of SAGA complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    colocalizes_with euchromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in polytene chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in polytene chromosome puff IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    transcriptional adaptor 3
    Names
    Ada3-PA
    Ada3-PC
    CG7098-PA
    CG7098-PC
    diskette

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      18085761..18088418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078671.5NP_523395.1  transcriptional adaptor 3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523395.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DN52, Q9VWZ1
      Related
      FBpp0074284
      Conserved Domains (1) summary
      pfam10198
      Location:413518
      Ada3; Histone acetyltransferases subunit 3
    2. NM_001272738.2NP_001259667.1  transcriptional adaptor 3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259667.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DN52, M9PHZ1
      Conserved Domains (1) summary
      pfam10198
      Location:413518
      Ada3; Histone acetyltransferases subunit 3