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    CG7115 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34069, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7115provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027515
    Locus tag
    Dmel_CG7115
    See related
    AllianceGenome:FB:FBgn0027515
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD21794; Dmel\CG7115; dPPM1L; PP2C
    Summary
    Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including adult head; germline cell; larval muscle system; and pole plasm. Orthologous to human PPM1L (protein phosphatase, Mg2+/Mn2+ dependent 1L). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7115 in Genome Data Viewer
    Location:
    28D1-28D1; 2-29 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7821151..7825350)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7821151..7825350)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene r2d2 Neighboring gene Cell division cycle 14 Neighboring gene LanB1 Neighboring gene antisense RNA:CR45008 Neighboring gene Receptor of activated protein kinase C 1 Neighboring gene microtubule star Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues. Parsons LM, et al. G3 (Bethesda), 2017 Aug 7. PMID 28611255, Free PMC Article
    2. An RNAi Screen To Identify Protein Phosphatases That Function Within the Drosophila Circadian Clock. Agrawal P, et al. G3 (Bethesda), 2016 Dec 7. PMID 27784754, Free PMC Article
    3. Genome-wide RNAi screen identifies broadly-acting host factors that inhibit arbovirus infection. Yasunaga A, et al. PLoS Pathog, 2014 Feb. PMID 24550726, Free PMC Article
    4. Genome-wide assessment of AU-rich elements by the AREScore algorithm. Spasic M, et al. PLoS Genet, 2012 Jan. PMID 22242014, Free PMC Article
    5. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cation binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7115-PA
    CG7115-PB
    CG7115-PC
    CG7115-PD
    CG7115-PE
    NP_001260214.1
    NP_001260215.1
    NP_001260216.1
    NP_609154.1
    NP_723320.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7821151..7825350
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273286.1 → NP_001260215.1  uncharacterized protein Dmel_CG7115, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260215.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCH3
      Conserved Domains (1) summary
      cd00143
      Location:58 → 429
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    2. NM_001273285.1 → NP_001260214.1  uncharacterized protein Dmel_CG7115, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260214.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D8FT19
      Conserved Domains (1) summary
      cd00143
      Location:56 → 427
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    3. NM_164774.3 → NP_723320.1  uncharacterized protein Dmel_CG7115, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723320.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XZ28
      Related
      FBpp0079146
      Conserved Domains (1) summary
      cd00143
      Location:111 → 482
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    4. NM_001273287.1 → NP_001260216.1  uncharacterized protein Dmel_CG7115, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260216.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XZ28
      Conserved Domains (1) summary
      cd00143
      Location:111 → 482
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    5. NM_135310.4 → NP_609154.1  uncharacterized protein Dmel_CG7115, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609154.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XZ28
      Related
      FBpp0079147
      Conserved Domains (1) summary
      cd00143
      Location:111 → 482
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D8FT19 D8FT19
    M9PCH3 M9PCH3
    Q9XZ28 Q9XZ28

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