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    dosC diguanylate cyclase DosC [ Shigella dysenteriae ]

    Gene ID: 75171576, updated on 3-Dec-2024

    Summary

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    Gene symbol
    dosC
    Gene description
    diguanylate cyclase DosC
    Locus tag
    HUZ68_RS11280
    Gene type
    protein coding
    Organism
    Shigella dysenteriae (strain: SWHEFF_49)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
    Old locus tag
    HUZ68_11160
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    Genomic context

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    NZ_CP055055.1Genomic Context describing neighboring genes Neighboring gene D-alanyl-D-alanine dipeptidase Neighboring gene pseudo Neighboring gene pseudo Neighboring gene glycoside hydrolase family 10 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP055055.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Important roles of Tyr43 at the putative heme distal side in the oxygen recognition and stability of the Fe(II)-O2 complex of YddV, a globin-coupled heme-based oxygen sensor diguanylate cyclase. Kitanishi K, et al. Biochemistry, 2010 Dec 14. PMID 21067162
    2. An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control. Tuckerman JR, et al. Biochemistry, 2009 Oct 20. PMID 19764732
    3. High-resolution genomic surveillance elucidates a multilayered hierarchical transfer of resistance between WWTP- and human/animal-associated bacteria. Che Y, et al. Microbiome, 2022 Jan 25. PMID 35078531, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    diguanylate cyclase DosC
    WP_000426292.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP055055.1 Reference assembly

      Range
      2357350..2358732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_000426292.1 MULTISPECIES: diguanylate cyclase DosC [Enterobacteriaceae]

      See identical proteins and their annotated locations for WP_000426292.1

      UniProtKB/Swiss-Prot
      P0AA89, P0AA90, P77793
      UniProtKB/TrEMBL
      A0A0H3PM46, A0A4P8C2R5, A0A7U9LP09, A0A9P2GNB6, A0A9Q6UZY1, A0AAN1AHE0, A0AAN3ZGK5, A0AAN4ILE0, A0AAV3HA00, A0AAV3I6W8, C3TA62
      Conserved Domains (2) summary
      cd14757
      Location:7 → 153
      GS_EcDosC-like_GGDEF; Globin sensor domain of Escherichia coli Direct Oxygen Sensing Cyclase and related proteins; coupled to a C-terminal GGDEF domain
      pfam00990
      Location:297 → 452
      GGDEF; Diguanylate cyclase, GGDEF domain
    Nucleotide Protein
    Heading Accession and Version

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