U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    pagA anthrax toxin protective antigen [ Bacillus anthracis str. 'Ames Ancestor' ]

    Gene ID: 45025512, updated on 6-Jun-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    pagA
    Gene description
    anthrax toxin protective antigen
    Locus tag
    GBAA_RS29110
    Gene type
    protein coding
    Organism
    Bacillus anthracis str. 'Ames Ancestor' (strain: Ames Ancestor; A2084)
    Lineage
    Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group
    Old locus tag
    GBAA_pXO1_0164
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    plasmid: pXO1
    Sequence:
    NC_007322.2 (143779..146073)

    NC_007322.2Genomic Context describing neighboring genes Neighboring gene spore germination protein GerXA Neighboring gene spore germination protein GerXC Neighboring gene hypothetical protein Neighboring gene transcriptional repressor PagR Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_007322.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The protective antigen component of anthrax toxin forms functional octameric complexes. Kintzer AF, et al. J Mol Biol, 2009 Sep 25. PMID 19627991, Free PMC Article
    2. Anthrax Protective Antigen Retargeted with Single-Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells. Loftis AR, et al. Chembiochem, 2020 Oct 1. PMID 32369652, Free PMC Article
    3. Bacillus anthracis Virulence Regulator AtxA Binds Specifically to the pagA Promoter Region. McCall RM, et al. J Bacteriol, 2019 Dec 1. PMID 31570528, Free PMC Article
    4. Anthrax lethal and edema toxins in anthrax pathogenesis. Liu S, et al. Trends Microbiol, 2014 Jun. PMID 24684968, Free PMC Article
    5. The complete genome sequence of Bacillus anthracis Ames "Ancestor". Ravel J, et al. J Bacteriol, 2009 Jan. PMID 18952800, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Anthrax Protective Antigen Retargeted with Single-Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells.
      Title: Anthrax Protective Antigen Retargeted with Single-Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells.
    2. Bacillus anthracis virulence regulator AtxA binds specifically to the pagA promoter region.
      Title: Bacillus anthracis Virulence Regulator AtxA Binds Specifically to the pagA Promoter Region.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General protein information

    Go to the top of the page Help
    Preferred Names
    anthrax toxin protective antigen

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007322.2 Reference assembly

      Range
      143779..146073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_000746486.1 MULTISPECIES: anthrax toxin protective antigen [Bacillus]

      See identical proteins and their annotated locations for WP_000746486.1

      UniProtKB/Swiss-Prot
      P13423, Q937W2, Q937W3, Q9F5R7, Q9KH69, Q9RQU2
      UniProtKB/TrEMBL
      A0A0F7RN95, Q52NH4
      Conserved Domains (4) summary
      pfam17475
      Location:289 → 506
      Binary_toxB_2; Clostridial binary toxin B/anthrax toxin PA domain 2
      pfam03495
      Location:205 → 286
      Binary_toxB; Clostridial binary toxin B/anthrax toxin PA Ca-binding domain
      pfam17476
      Location:509 → 610
      Binary_toxB_3; Clostridial binary toxin B/anthrax toxin PA domain 3
      pfam07691
      Location:44 → 179
      PA14; PA14 domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.